Shabsigh R, Fishman I J, Schum C, Dunn J K
Scott Department of Urology, Baylor College of Medicine, Houston, Texas.
Urology. 1991 Sep;38(3):227-31. doi: 10.1016/s0090-4295(91)80350-g.
A total of 132 consecutive patients with erectile impotence underwent extensive evaluation, including vascular evaluation with intracavernous injection of papaverine and penile duplex ultrasonography, to determine the etiology of impotence. Three vascular risk factors, smoking, diabetes mellitus and hypertension, were investigated for their impact on vasculogenic impotence. The patients were divided into four groups: one with no risk factors, one with one vascular risk factor, one with two vascular risk factors, and one with all three risk factors. The results of penile vascular evaluation in these patient groups were compared. The incidence of penile vascular impairment was found to be higher in patients with one vascular risk factor than in those with none. The proportion of abnormal penile vascular findings significantly increased as the number of risk factors increased. These data confirm the important role of vascular risk factors, smoking, diabetes mellitus, and hypertension, in the pathogenesis of organic impotence.
总共132例连续性勃起功能障碍患者接受了全面评估，包括海绵体内注射罂粟碱及阴茎双功能超声检查进行血管评估，以确定阳痿的病因。研究了吸烟、糖尿病和高血压这三种血管危险因素对血管性阳痿的影响。患者被分为四组：一组无危险因素，一组有一个血管危险因素，一组有两个血管危险因素，一组有所有三个危险因素。比较了这些患者组阴茎血管评估的结果。发现有一个血管危险因素的患者阴茎血管损伤的发生率高于无危险因素的患者。随着危险因素数量的增加，阴茎血管异常发现的比例显著增加。这些数据证实了血管危险因素，即吸烟、糖尿病和高血压，在器质性阳痿发病机制中的重要作用。
