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[当今颈动脉手术的现状:技术、适应症、结果]

[The status of carotid artery surgery today: technique, indications, results].

作者信息

Polterauer P, Prager M, Kretschmer G, Huk I

机构信息

I. Chirurgischen Universitätsklinik Wien.

出版信息

Acta Med Austriaca. 1991;18(2):51-5.

PMID:1887736
Abstract

Carotid artery endarterectomy (CAE) is a surgical standard procedure today. The indication is the symptomatic patient (Stage II) with transient ischemic attacks (TIA) and stenosis of the internal carotid artery (ACI). Data of several studies have yielded a highly restrictive policy toward operative procedures in asymptomatic patients (Stage I) with carotid bruit or ACI-stenosis. Furthermore there emerged wide consensus, that patients with frank stroke (Stage III) should not be operated upon. As diagnostic procedures highly advanced non invasive procedures came up during the last decade, as well as computerized tomography and digital subtraction angiography. The operative procedure is performed in general anesthesia with controlled hypertension during the clamping period (n = 650). Perioperative results without using a shunt are not different to those with a shunt. During the last 5 year period our results yielded a 1% perioperative central permanent neurological deficit rate (CPNDR) and a 1% operative mortality. During a 51 months median observation period 1.5% presented again with transient ischemic attacks-with TIA; 0.6% developed a stroke and 2.2% deceased by cerebral complications yielding at totally 4.3% long term complication rate. The annual rates are 0.3%, 0.1% respectively 0.5%, totally 0.9%. In conclusion CAE can be offered as a safe surgical stroke preventing procedure in symptomatic TIA patients with ACI stenoses in our institution. Perioperative as well as long term results are yielding a high standard and are clearly better than those without operation.

摘要

颈动脉内膜切除术(CAE)是目前的一种外科标准手术。其适应症为有症状的患者(II期),伴有短暂性脑缺血发作(TIA)和颈内动脉(ACI)狭窄。多项研究的数据显示,对于有颈动脉杂音或ACI狭窄的无症状患者(I期),手术操作的政策非常严格。此外,对于明确患有中风的患者(III期)不应进行手术这一点已达成广泛共识。在过去十年中,随着计算机断层扫描和数字减影血管造影等先进的非侵入性诊断程序的出现。手术在全身麻醉下进行,夹闭期控制高血压(n = 650)。不使用分流器的围手术期结果与使用分流器的结果并无差异。在过去5年期间,我们的结果显示围手术期永久性中枢神经功能缺损率(CPNDR)为1%,手术死亡率为1%。在51个月的中位观察期内,1.5%的患者再次出现短暂性脑缺血发作(TIA);0.6%的患者发生中风,2.2%的患者因脑部并发症死亡,长期并发症发生率总计为4.3%。年发生率分别为0.3%、0.1%和0.5%,总计0.9%。总之,在我们机构中,对于有ACI狭窄的有症状TIA患者,CAE可作为一种安全的预防中风的外科手术提供。围手术期以及长期结果都达到了很高的标准,明显优于未手术的结果。

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