以色列亚急性硬化性全脑炎患者的人类白细胞抗原（HLA）抗原

HLA antigens in subacute sclerosing panencephalitis patients in Israel.

作者信息

Kahana E, Brautbar C

机构信息

Neurology Unit, Barzilai Medical Center, Ashkelon, Israel.

出版信息

Acta Neurol Scand. 1991 Jun;83(6):367-9. doi: 10.1111/j.1600-0404.1991.tb03965.x.

DOI:10.1111/j.1600-0404.1991.tb03965.x

PMID:1887759

Abstract

HLA Class I antigens were determined in the 49 subacute sclerosing panencephalitis (SSPE) patients. In analyzing the Arabs and the Jews separately, there is a decrease in HLA-A2 in the Jewish patients (X2 = 3.96; P less than 0.05), a significant increase in the HLA-A29 in the Arab SSPE patients (X2 = 6.29; P less than 0.02), and a slight, insignificant increase of HLA-A29 in the Jewish patients. The present study supports previous findings of Kurent's and needs following studies in larger groups of Arab SSPE patients.

摘要

对49例亚急性硬化性全脑炎（SSPE）患者进行了I类人类白细胞抗原（HLA）检测。分别分析阿拉伯人和犹太人时发现，犹太患者中HLA - A2降低（X2 = 3.96；P＜0.05），阿拉伯SSPE患者中HLA - A29显著增加（X2 = 6.29；P＜0.02），而犹太患者中HLA - A29有轻微但不显著的增加。本研究支持了库伦特之前的研究结果，并且需要对更多阿拉伯SSPE患者群体进行后续研究。