亚急性硬化性全脑炎中的人类白细胞抗原（HLA）和补体C4

HLA and C4 in subacute sclerosing panencephalitis.

作者信息

Harada F, Onisawa S, Suzuki K, Matsumoto H, Sasazuki T

机构信息

Department of Genetics, Kyushu University, Fukuoka, Japan.

出版信息

Tissue Antigens. 1987 Aug;30(2):73-5. doi: 10.1111/j.1399-0039.1987.tb01600.x.

DOI:10.1111/j.1399-0039.1987.tb01600.x

PMID:3672494

Abstract

The frequencies of HLA-A, B, C, DR and DQ antigens were studied in 63 Japanese patients with subacute sclerosing panencephalitis (SSPE). The results could not confirm the statistical association between SSPE and HLA antigens. In addition, the allele frequencies of complement components C4, C2 and BF were determined in the 20 haplotypes with 10 unrelated SSPE patients. A significant association of C4A QO with SSPE in Caucasians was not found in Japanese.

摘要

对63例日本亚急性硬化性全脑炎（SSPE）患者的HLA - A、B、C、DR和DQ抗原频率进行了研究。结果未能证实SSPE与HLA抗原之间存在统计学关联。此外，还对10例无亲缘关系的SSPE患者的20种单倍型中的补体成分C4、C2和BF的等位基因频率进行了测定。在日本人中未发现白种人中C4A QO与SSPE之间的显著关联。