Savino J S, Troianos C A, Aukburg S, Weiss R, Reichek N
Department of Anesthesia, University of Pennsylvania, Philadelphia 19104.
Anesthesiology. 1991 Sep;75(3):445-51. doi: 10.1097/00000542-199109000-00011.
Transesophageal echocardiography permits measurement of the pulmonary artery diameter (two-dimensional echocardiography) and pulmonary artery blood flow velocity (pulsed-wave Doppler). These measurements considered with the heart rate allow for the determination of pulmonary artery blood flow, which is equivalent to cardiac output. This study compared the precision of transesophageal Doppler-derived cardiac output (DdCO) with the precision of thermodilution cardiac output (TdCO) and examined the agreement between DdCO and TdCO in 33 cardiac surgical patients. The proximal pulmonary artery diameter was measured in triplicate during systole and end expiration, and the local blood flow velocity was recorded on video tape. The instantaneous pulmonary artery blood flow velocity (centimeters per second) for three random cardiac beats was integrated with respect to time. DdCO was calculated as the product of the flow velocity integral (centimeters per beat), heart rate (beats per min), and the mean cross-sectional area (centimeters squared) of the main pulmonary artery. At the same time that the velocity recordings were made, three serial determinations of TdCO were made by an independent observer. Pulmonary blood flow could be measured in 25 of the 33 patients. The anatomical relationship among the esophagus, the left main stem bronchus, and the pulmonary artery did not allow adequate imaging of the pulmonary artery in 8 (24%) of the patients. A total of 45 sets of triplicate measurements were made. The range of cardiac outputs encountered was 1.7-6.6 l.min-1 by TdCO and 1.5-6.9 l.min-1 by DdCO. The 95% confidence limits for the difference between the two methods (agreement) was 0.030 +/- 0.987 l.min-1.(ABSTRACT TRUNCATED AT 250 WORDS)
经食管超声心动图可测量肺动脉直径(二维超声心动图)和肺动脉血流速度(脉冲波多普勒)。结合心率对这些测量值进行分析,可确定肺动脉血流量,而肺动脉血流量等同于心输出量。本研究比较了经食管多普勒心输出量(DdCO)与热稀释法心输出量(TdCO)的测量精度,并在33例心脏手术患者中检验了DdCO与TdCO之间的一致性。在收缩期和呼气末对近端肺动脉直径进行三次测量,并将局部血流速度记录在录像带上。对三个随机心动周期的瞬时肺动脉血流速度(厘米/秒)进行时间积分。DdCO的计算方法为流速积分(厘米/搏)、心率(次/分钟)与主肺动脉平均横截面积(平方厘米)的乘积。在记录流速的同时,由一名独立观察者对TdCO进行三次连续测定。33例患者中有25例可测量肺血流量。8例(24%)患者的食管、左主支气管与肺动脉之间的解剖关系导致无法对肺动脉进行充分成像。共进行了45组三次测量。TdCO测得的心输出量范围为1.7 - 6.6升/分钟,DdCO测得的心输出量范围为1.5 - 6.9升/分钟。两种方法之间差异的95%置信区间(一致性)为0.030±0.987升/分钟。(摘要截取自250字)