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兔实验性局灶性脑缺血时的脑电图变化与血小板聚集

EEG changes and platelet aggregation in experimental cerebral focal ischemia in rabbits.

作者信息

Bo P, Cosi V, Taccola A, Romani A, Savoldi F

机构信息

Istituto Neurologico C. Mondino, Universita di Pavia, Italy.

出版信息

Boll Soc Ital Biol Sper. 1991 Jan;67(1):71-5.

PMID:1888474
Abstract

Nine white New Zealand rabbits were submitted to internal carotid embolization with microspheres which caused a histologically verified focal cerebral ischemia. Six animals were sham-operated. EEG, QEEG, ECG, blood pressure, rectal temperature and platelet aggregation were monitored in basal conditions and one hour after ischemia. Embolized animals showed an increase in power density spectrum (PDS) and delta activity (0.15-3.70 Hz) and the appearance of platelet aggregation. The QEEG changes were correlated to the degree of platelet aggregation after ischemia.

摘要

九只白色新西兰兔接受了微球栓塞颈内动脉手术,造成了经组织学证实的局灶性脑缺血。六只动物接受了假手术。在基础状态和缺血一小时后监测脑电图(EEG)、定量脑电图(QEEG)、心电图(ECG)、血压、直肠温度和血小板聚集情况。栓塞动物的功率密度谱(PDS)和δ活动(0.15 - 3.70赫兹)增加,并且出现了血小板聚集。定量脑电图的变化与缺血后血小板聚集程度相关。

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