Garrison C Z, Addy C L, Jackson K L, McKeown R E, Waller J L
Department of Epidermiology and Biostatistics, University of South Carolina, Columbia 29208.
J Am Acad Child Adolesc Psychiatry. 1991 Jul;30(4):636-41. doi: 10.1097/00004583-199107000-00017.
The performance of the Center for Epidemiologic Studies Depression Scale (CES-D) as a screen for depression was explored in a two-stage epidemiological study of adolescents. The study consisted of a CES-D screening stage completed by a school sample of 2,465 young adolescents and a structured psychiatric interview stage completed by 332 mother-adolescent pairs. Adolescents with interview validated depression had elevated screening scores (mean = 31.10, SD = 11.30) compared with individuals with no disorder (mean = 21.01, SD = 11.77). Using receiver operating characteristic curves, a cut point of 12 for males produced the best overall screening characteristics (sensitivity = 0.85, specificity = 0.49), while for females, a cut point of 22 was optimal (sensitivity = 0.83, specificity = 0.77).
在一项针对青少年的两阶段流行病学研究中，探讨了流行病学研究中心抑郁量表（CES-D）作为抑郁症筛查工具的性能。该研究包括一个由2465名青少年学生样本完成的CES-D筛查阶段，以及一个由332对母亲-青少年完成的结构化精神科访谈阶段。与无精神障碍的个体（均值=21.01，标准差=11.77）相比，经访谈验证患有抑郁症的青少年筛查得分更高（均值=31.10，标准差=11.30）。使用受试者工作特征曲线，男性的最佳总体筛查特征切点为12（灵敏度=0.85，特异度=0.49），而女性的最佳切点为22（灵敏度=0.83，特异度=0.77）。
