Ishida T, Matsumura Y, Miyake A, Yokoi T
Department of Internal Medicine, Kurashiki Central Hospital, Okayama, Japan.
Kekkaku. 1991 Jul;66(7):493-7.
A 78 year-old female was referred to our hospital, because diffuse miliary shadows in bilateral lung fields were discovered during upper G.I. series. She did not complain of fever or display any chest symptoms. Her laboratory data on admission revealed mild hypoxemia and high serum CA 19-9. The transbronchial lung biopsy specimen proved epithelioid cell granulomas. M. tuberculosis was observed on culture from the sputa, urine and bronchoalveolar lavage fluid. She was diagnosed to have miliary tuberculosis, and antituberculous drugs were administered. After the antituberculous therapy, the diffuse miliary shadows on the chest X-ray diminished gradually, and the laboratory data improved. No elevation in the body temperature was seen during the entire clinical course. Though it is known that miliary tuberculosis in elderly patients is often atypical and has mild symptoms, miliary tuberculosis without fever is very rare.
一名78岁女性因上消化道造影时发现双肺野弥漫性粟粒状阴影而转诊至我院。她没有发热主诉,也无任何胸部症状。入院时实验室检查显示轻度低氧血症及血清CA 19-9升高。经支气管肺活检标本证实为上皮样细胞肉芽肿。痰液、尿液及支气管肺泡灌洗液培养发现结核分枝杆菌。她被诊断为粟粒型肺结核,并接受抗结核药物治疗。抗结核治疗后,胸部X线片上的弥漫性粟粒状阴影逐渐消退,实验室检查结果也有所改善。整个临床过程中体温未升高。虽然已知老年患者粟粒型肺结核常不典型且症状较轻,但无发热的粟粒型肺结核非常罕见。