Baker K R, Drutz H P, Barnes M D
Gynecological Urology and Urodynamic Investigative Unit, Mount Sinai Hospital, Toronto, Ontario, Canada.
Am J Obstet Gynecol. 1991 Sep;165(3):679-81.
One hundred twenty-four women with chronic, persistent lower urinary tract symptoms who had been scheduled for elective urodynamic investigations at Mount Sinai's Urodynamic Investigative Unit were divided into two blind, randomized groups, receiving either a placebo or prophylactic antibiotic. At the time of urodynamic testing, the rate of unsuspected urinary tract infection was 8.1%. There was no statistically significant decrease in postinstrumentation infection rate in the group who received prophylactic antibiotics. We conclude that, given in the fashion described in the study, prophylactic antibiotics are not effective in preventing urinary tract infections caused by urodynamic testing.
124名患有慢性持续性下尿路症状的女性，她们原本计划在西奈山尿动力学研究单位进行选择性尿动力学检查，被分为两个随机双盲组，分别接受安慰剂或预防性抗生素治疗。在进行尿动力学检查时，未被怀疑的尿路感染率为8.1%。接受预防性抗生素治疗的组在器械检查后感染率没有统计学上的显著下降。我们得出结论，按照研究中描述的方式给予预防性抗生素，对预防尿动力学检查引起的尿路感染无效。
