Samarina I V, Taran I F, Proskurina V A, Liapustina L V
Antibiot Khimioter. 1991 Apr;36(4):22-3.
In vitro activity of 13 antibiotics and drug preparations as well as some of their combinations was studied with respect to Brucella melitensis. It was shown that the strains of B. melitensis were sensitive to sisomicin, amikacin, gentamicin, cefotaxime, rifaprim +, nitroxoline and trimethoprim. Variations in the doxycycline sensitivity depending on the strain were observed. The strains of B. melitensis were resistant to cephalexin, phosphomycin, chinoxydine, dioxydine and oxolinic acid. Combinations of sisomicin and trimethoprim at a ratio of 1:10 and sisomicin and nitroxoline at a ratio of 1:2 had a summation effect.
研究了13种抗生素及药物制剂及其某些组合对羊布鲁氏菌的体外活性。结果表明，羊布鲁氏菌菌株对西索米星、阿米卡星、庆大霉素、头孢噻肟、利福普明+、硝羟喹啉和甲氧苄啶敏感。观察到不同菌株对多西环素的敏感性存在差异。羊布鲁氏菌菌株对头孢氨苄、磷霉素、喹乙醇、二氧喹啉和恶喹酸耐药。西索米星与甲氧苄啶以1:10的比例组合以及西索米星与硝羟喹啉以1:2的比例组合具有相加作用。
