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关于后交叉韧带撕裂的临床研究设计薄弱。

Clinical studies on posterior cruciate ligament tears have weak design.

作者信息

Watsend Anne Marie Eriksen, Osestad Toril M Ø, Jakobsen Rune B, Engebretsen Lars

机构信息

Orthopaedic Center, Ullevaal University Hospital and Medical School, University of Oslo, Oslo 0407, Norway.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2009 Feb;17(2):140-9. doi: 10.1007/s00167-008-0632-9. Epub 2008 Oct 17.

Abstract

Very few studies in the literature focus on isolated PCL injury. Recent studies are in general more optimistic with regard to the results than previous reports. There are few randomized controlled trials and few prospective comparative studies, which may limit the value of the reported results. The goal of the present study was to evaluate the methodology of published studies according to a well-established scoring system. Studies with a high success rate have a low score on methodology design. This study was based on systematic review and level 3 evidence. We performed a literature search and included studies in which the primary aim was to report the outcome after management of isolated PCL injury. The quality of the studies was evaluated using a modified Coleman methodology score, which results in a score between 0 and 100. Studies were also assessed with use of level-of-evidence rating. We collected data on the year of publication, reported results after surgery and conservative treatment, and the outcome scales used to assess the results. Forty studies were included. The average methodology score was 52. No significant difference in outcome was detected between conservative and surgical management. Our hypothesis that a low Coleman score would yield a good clinical result was not verified. This could be caused by the fact that there were very few studies with a high Coleman score. The Coleman methodology score correlated positively with the year of publication and with the level-of-evidence rating. In the 40 reported studies, 12 different outcome scales were used. In conclusion, the generally low methodological quality shows that caution is required when interpreting results after management of injury to the PCL. Firm recommendations on what treatment to choose cannot be given at this time on the basis of these studies. More attention should be paid to methodological quality when designing, conducting and reporting trials.

摘要

文献中很少有研究聚焦于单纯的后交叉韧带(PCL)损伤。近期的研究总体上比之前的报告对结果更为乐观。随机对照试验和前瞻性比较研究较少,这可能限制了所报道结果的价值。本研究的目的是根据一个成熟的评分系统评估已发表研究的方法学。成功率高的研究在方法学设计上得分较低。本研究基于系统评价和3级证据。我们进行了文献检索,纳入的研究其主要目的是报告单纯PCL损伤处理后的结果。使用改良的科尔曼方法学评分评估研究质量,评分结果在0到100分之间。还使用证据等级评定对研究进行评估。我们收集了关于发表年份、手术和保守治疗后报告的结果以及用于评估结果的结局量表的数据。共纳入40项研究。平均方法学评分为52分。未发现保守治疗和手术治疗在结果上有显著差异。我们关于科尔曼评分低会产生良好临床结果的假设未得到证实。这可能是因为科尔曼评分高的研究非常少。科尔曼方法学评分与发表年份和证据等级评定呈正相关。在40项报告的研究中,使用了12种不同的结局量表。总之,总体较低的方法学质量表明,在解释PCL损伤处理后的结果时需要谨慎。基于这些研究,目前无法就选择何种治疗给出确切建议。在设计、开展和报告试验时,应更加关注方法学质量。

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