Bodden Denise H M, Dirksen Carmen D, Bögels Susan M, Nauta Maaike H, De Haan Else, Ringrose Jaap, Appelboom Carla, Brinkman Andries G, Appelboom-Geerts Karen C M M J
University of Utrecht, The Netherlands.
Clin Child Psychol Psychiatry. 2008 Oct;13(4):543-64. doi: 10.1177/1359104508090602.
The objective of this study was to investigate the cost-effectiveness of family cognitive-behavioral therapy (CBT) compared with individual CBT in children with anxiety disorders. Clinically anxious children (aged 8-18 years) referred for treatment were randomly assigned to family or individual CBT and were assessed pre-treatment, post treatment, and at 3 months and 1 year after treatment. Cost-effectiveness ratios were calculated expressing the incremental costs per anxiety-free child and the incremental costs per Quality Adjusted Life Year (QALY) for the referred child. Neither societal costs nor effectiveness were significantly different between individual and family CBT. However, the point estimates of the cost-effectiveness ratios resulted in dominance for individual CBT, indicating that individual CBT is more effective and less costly than family CBT. These results were confirmed by bootstrap analyses and cost-effectiveness acceptability curves. Several secondary and sensitivity analyses showed that the results were robust. It can be concluded that family CBT is not a cost-effective treatment for clinically anxious children, compared with individual CBT.
本研究的目的是调查与个体认知行为疗法(CBT)相比,家庭认知行为疗法对焦虑症儿童的成本效益。被转诊接受治疗的临床焦虑儿童(8至18岁)被随机分配到家庭或个体CBT组,并在治疗前、治疗后、治疗后3个月和1年进行评估。计算成本效益比,以表示每个无焦虑儿童的增量成本以及每个转诊儿童的质量调整生命年(QALY)的增量成本。个体CBT和家庭CBT在社会成本和效果方面均无显著差异。然而,成本效益比的点估计结果显示个体CBT占优势,这表明个体CBT比家庭CBT更有效且成本更低。这些结果通过自助法分析和成本效益可接受性曲线得到了证实。多项次要分析和敏感性分析表明结果是稳健的。可以得出结论,与个体CBT相比,家庭CBT对临床焦虑儿童而言并非具有成本效益的治疗方法。