Bakalli Aurora, Osmani Behxhet, Kamberi Lulzim, Pllana Ejup
University Clinical Center of Kosova, Department of Cardiology, Prishtine, Kosove.
Cases J. 2008 Oct 17;1(1):246. doi: 10.1186/1757-1626-1-246.
Tuberculous coronaritis is known to be a very rare phenomenon, although Mycobacterium tuberculosis, as some other infectious agents, may also act in the coronary vessels by activating the inflammatory mechanism of atherosclerosis. The association between active pulmonary tuberculosis and acute myocardial infarction has not been reported for around three and a half decades.
We presented here a case of a young, 30 year old, Caucasian woman who presented to Emergency Ward with severe chest pain, ECG and enzyme profile typical for acute myocardial infarction. Chest X-ray displayed high intensity shades in the left lung field, which after additional laboratory tests were shown to be due to active pulmonary tuberculosis.
As the patient did not have any other known coronary artery disease risk factors, we held responsible Mycobacterium tuberculosis for occurrence of acute myocardial infarction in this young female patient. We believe that the presentation of this rare case of myocardial infarction in a patient with active pulmonary tuberculosis should encourage researchers to investigate the potential role of Mycobacterium tuberculosis in pathogenesis of coronary heart disease.
已知结核性冠状动脉炎是一种非常罕见的现象,尽管结核分枝杆菌与其他一些感染因子一样,也可能通过激活动脉粥样硬化的炎症机制作用于冠状动脉血管。大约三十五年以来,活动性肺结核与急性心肌梗死之间的关联尚未见报道。
我们在此呈现一例30岁的年轻白人女性病例,该患者因严重胸痛就诊于急诊科,心电图和酶谱表现为典型的急性心肌梗死。胸部X线显示左肺野有高密度阴影,进一步实验室检查表明这是由活动性肺结核所致。
由于该患者没有任何其他已知的冠状动脉疾病危险因素,我们认为结核分枝杆菌是导致这位年轻女性患者发生急性心肌梗死的原因。我们相信,这例活动性肺结核患者发生罕见心肌梗死病例的呈现,应促使研究人员去探究结核分枝杆菌在冠心病发病机制中的潜在作用。