Kuang Haixue, Sun Shiwei, Yang Bingyou, Xia Yonggang, Feng Weisheng
Heilongjiang University of Chinese Medicine, Harbin 150040, PR China.
Fitoterapia. 2009 Jan;80(1):35-8. doi: 10.1016/j.fitote.2008.09.007. Epub 2008 Oct 6.
A new megastigmane sesquiterpene glucoside named chaihuxinoside A (1), and a new indole diglucoside named chaihuxinoside B (9) were isolated from the aerial parts of Bupleurum chinense DC. along with eight known compounds. Structures of two new compounds were elucidated by a combination of chemical and spectroscopic methods. Chaihuxinosides A and B were characterized as 11-hydroxyl-4-en-3,9-dioxo- megastigmane-11-O-beta-D-glucopyranoside (1), and 3-carboxy-indole-10-O-beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranosyl ester (9), respectively.
从柴胡地上部分分离得到一个新的巨大戟烷型倍半萜糖苷柴胡新苷A（1）和一个新的吲哚二糖苷柴胡新苷B（9），以及八个已知化合物。通过化学和光谱方法相结合阐明了这两个新化合物的结构。柴胡新苷A和B分别被鉴定为11-羟基-4-烯-3,9-二氧代-巨大戟烷-11-O-β-D-吡喃葡萄糖苷（1）和3-羧基吲哚-10-O-β-D-吡喃葡萄糖基（1→2）-β-D-吡喃葡萄糖酯（9）。
