从刺儿菜的地上部分中分离得到的一个新的羽扇豆烷型糖苷。

A new megastigmane glycoside from the aerial parts of Cirsium setosum.

机构信息

Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin 150040, China.

出版信息

Chin J Nat Med. 2013 Sep;11(5):534-7. doi: 10.1016/S1875-5364(13)60097-7.

DOI:10.1016/S1875-5364(13)60097-7

PMID:24359780

Abstract

AIM

To study the chemical constituents of the aerial parts of Cirsium setosum (Willd.) MB..

METHODS

The chemical constituents were isolated and purified by various chromatographic techniques. Their structures were determined on the basis of physical properties and spectroscopic data.

RESULTS

A new megastigmane glycoside and six known compounds were obtained and identified as (7E, 9R)-9-hydroxy-5, 7-megastigmadien-4-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyanoside (1), (6R, 7E, 9R)-9-hydroxy-4, 7-megastigmadien-3-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (2), urolignoside (3), 4, 9, 9'-trihydroxy-3, 3'-dimethoxy-8-O-4$\prime $-neolignan-7-O-β-D-glucopyranoside (4), citroside A (5), salidrosidin (6), and adenosine (7).

CONCLUSION

Compound 1 is a new megastigmane glycoside, named as Xiaojiglycoside A.

摘要

目的

研究小蓟地上部分的化学成分。

方法

采用各种色谱技术分离和纯化化学成分。根据物理性质和光谱数据确定其结构。

结果

从其中分离得到 1 个新的大柱烷型糖苷和 6 个已知化合物，分别鉴定为（7E，9R）-9-羟基-5，7-大柱烷二烯-4-酮-9-O-α-L-阿拉伯吡喃糖苷基-（1→6）-β-D-吡喃葡萄糖苷（1）、（6R，7E，9R）-9-羟基-4，7-大柱烷二烯-3-酮-9-O-α-L-阿拉伯吡喃糖苷基-（1→6）-β-D-吡喃葡萄糖苷（2）、乌洛苷（3）、4、9、9′-三羟基-3、3′-二甲氧基-8-O-4′-新木脂素-7-O-β-D-吡喃葡萄糖苷（4）、枸橼苷 A（5）、红景天苷（6）和腺苷（7）。