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[兔右心房大折返形成的实验分析]

[Experimental analysis of the formation of macro-reentry in the right atrium of rabbits].

作者信息

Bukauskas F F, Valiunas V A, Mizeras V A, Tamoshiavichius A P

出版信息

Biull Eksp Biol Med. 1991 Apr;111(4):355-9.

PMID:1893129
Abstract

The aim of the present study was experimental demonstration of the formation of reentry in isolated preparations of the rabbit's right atrium, including sulcus terminalis, interatrial septum and AV node. Tachycardia was evoked by extrasystolic stimulation of the preparation. Reentry was identified by computerized multichannel mapping of excitation wave propagation. A series of sections performed in the area between the caval veins and the coronary sinus confirmed the presence of reentry pathway round the orifices of caval veins and through AV made zone. Local cooling and sections performed in different parts of the AV node showed that not all areas of AV node were involved in the formation of reentry, but only the perinodal (AN) area. These effects on the AN area terminated tachycardia. Linear dependence between the period of tachycardia and delay in the AV nodal zone was found.

摘要

本研究的目的是通过实验证明在兔右心房的离体标本(包括终沟、房间隔和房室结)中折返的形成。通过对标本进行期外刺激诱发心动过速。通过对兴奋波传播进行计算机化多通道标测来识别折返。在腔静脉和冠状窦之间的区域进行的一系列切片证实了围绕腔静脉口并穿过房室交界区存在折返路径。在房室结不同部位进行的局部冷却和切片显示,并非房室结的所有区域都参与折返的形成,只有结周(AN)区域参与。对AN区域的这些作用终止了心动过速。发现心动过速的周期与房室结区延迟之间存在线性关系。

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