[人类心肌细胞中的蛋白质质量与基因含量不对应]
[Protein mass in human cardiomyocytes does not correspond to gene content].
作者信息
Vasil'eva I A, Brodskiĭ V Ia, Sarkisov D S, Panova N V
出版信息
Biull Eksp Biol Med. 1991 Jun;111(6):652-3.
PMID:1893201
Abstract
Lack of proportionality between DNA and protein content has been revealed in the human cardiac myocytes. The proportion 2:4:8:16 was observed in DNA of di-, tetra-, octa- and hexadeca myocytes while the protein content of the same cells was 2:3.5:5.2:7.2 in the inner layer, 2:3.5:6.5:8.9 in the central layer and 2:3.1:5.6:9.1 in the outer layer of the normal left ventricle. The protein content of myocytes of the same ploidy was higher in the inner layer than in other ones.
摘要
在人类心肌细胞中已发现DNA与蛋白质含量之间缺乏比例关系。在二倍体、四倍体、八倍体和十六倍体心肌细胞的DNA中观察到2:4:8:16的比例，而在正常左心室的内层、中层和外层中，相同细胞的蛋白质含量分别为2:3.5:5.2:7.2、2:3.5:6.5:8.9和2:3.1:5.6:9.1。相同倍性的心肌细胞的蛋白质含量在内层高于其他层。
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