Minsky B D, Cohen A M, Hajdu S I
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
Cancer. 1991 Oct 1;68(7):1640-3. doi: 10.1002/1097-0142(19911001)68:7<1640::aid-cncr2820680729>3.0.co;2-6.
Leiomyosarcomas of the large intestine are unusual neoplasms, comprising less than 0.1% of all malignancies of the colon and rectum. Six cases of leiomyosarcoma of the anus have been reported. The optimal treatment for this neoplasm is not known. The standard surgical approach is abdominoperineal resection. The authors report the seventh case of this rare neoplasm and outline its treatment using local excision and iridium 192 brachytherapy in an attempt to preserve the anal sphincter. In selected patients, conservative surgery followed by radiation therapy may be an alternative to radical surgery, with the goals of local control of the disease and anal sphincter preservation. However, more experience is needed before this approach could be recommended routinely.
大肠平滑肌肉瘤是一种罕见的肿瘤，占结肠和直肠所有恶性肿瘤的比例不到0.1%。肛门平滑肌肉瘤已有6例报道。目前尚不清楚该肿瘤的最佳治疗方法。标准的手术方式是腹会阴联合切除术。作者报告了第7例这种罕见肿瘤，并概述了采用局部切除和铱192近距离放射治疗以保留肛门括约肌的治疗方法。在部分患者中，保守手术联合放疗可能是根治性手术的替代方案，目标是局部控制疾病并保留肛门括约肌。然而，在常规推荐这种方法之前，还需要更多的经验。
