使用原子力显微镜测量前列腺癌细胞的弹性特性。
Measurement of elastic properties of prostate cancer cells using AFM.
作者信息
Faria Elsa Correia, Ma Nan, Gazi Ehsan, Gardner Peter, Brown Mick, Clarke Noel W, Snook Richard D
机构信息
School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, UK.
出版信息
Analyst. 2008 Nov;133(11):1498-500. doi: 10.1039/b803355b. Epub 2008 Jul 25.
DOI:10.1039/b803355b
PMID:18936825
Abstract
This communication reports that three prostate cancer cells of differing metastatic potential were discriminated based on their Young's moduli (LNCaP - 287 +/- 52 N m(-2), PC-3 - 1401 +/- 162 N m(-2) and BPH - 2797 +/- 491 N m(-2)) which were determined using AFM and the Hertz model.
摘要
本通讯报道，根据使用原子力显微镜（AFM）和赫兹模型测定的杨氏模量，区分了三种具有不同转移潜能的前列腺癌细胞（LNCaP - 287 ± 52 N m(-2)，PC-3 - 1401 ± 162 N m(-2)和BPH - 2797 ± 491 N m(-2)）。
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