Johnston Kevin, Everling Stefan
Centre for Neuroscience Studies, Queen's University, Kingston, Ont., Canada K7L 3N6.
Brain Cogn. 2008 Dec;68(3):271-83. doi: 10.1016/j.bandc.2008.08.017. Epub 2008 Oct 21.
A multitude of cognitive functions can easily be tested by a number of relatively simple saccadic eye movement tasks. This approach has been employed extensively with patient populations to investigate the functional deficits associated with psychiatric disorders. Neurophysiological studies in non-human primates performing the same tasks have begun to provide us with insights into the neural mechanisms underlying many cognitive functions. Here, we review studies that have investigated single neuron activity in the superior colliculus (see glossary), frontal eye field, supplementary eye field, dorsolateral prefrontal cortex, anterior cingulate (see glossary) cortex and lateral intraparietal area associated with the performance of visually guided saccades, anti-saccades and memory-guided saccades in awake behaving monkeys.
许多认知功能可以通过一些相对简单的扫视眼动任务轻松进行测试。这种方法已广泛应用于患者群体，以研究与精神疾病相关的功能缺陷。对执行相同任务的非人类灵长类动物进行的神经生理学研究已开始为我们提供对许多认知功能背后神经机制的见解。在此，我们回顾了一些研究，这些研究调查了清醒行为猴子在执行视觉引导扫视、反扫视和记忆引导扫视时，上丘（见术语表）、额叶眼区、辅助眼区、背外侧前额叶皮层、前扣带回（见术语表）皮层和顶内沟外侧区域的单个神经元活动。
