心脏手术后巨细胞病毒诱导的溶血性贫血
Cytomegalovirus-induced haemolytic anaemia after cardiac surgery.
作者信息
Holt S, Kirkham N
出版信息
Thorax. 1976 Dec;31(6):786-8. doi: 10.1136/thx.31.6.786.
Abstract
A patient, who underwent aortic valve replacement, developed a transient, autoimmune haemolytic anaemia in association with a significant rise in titre of antibodies against cytomegalovirus. A serological survey of blood donors indicated that the source of infection was fresh blood transfused during and shortly after surgery. A number of cases of short-lived haemolytic anaemia after large volume blood transfusion with cardiac surgery may be explained by this mechanism. It may be preferable to use only blood that has been screened for evidence of recent cytomegalovirus infection if post-perfusion complications of this disease are to be avoided.
摘要
一名接受主动脉瓣置换术的患者出现了短暂的自身免疫性溶血性贫血，同时抗巨细胞病毒抗体滴度显著升高。对献血者的血清学调查表明，感染源是手术期间及术后不久输入的新鲜血液。心脏手术大量输血后出现的一些短期溶血性贫血病例可能可用这种机制来解释。如果要避免这种疾病的灌注后并发症，最好仅使用经过筛查以寻找近期巨细胞病毒感染证据的血液。
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