献血者中的潜伏性巨细胞病毒感染。
Latent cytomegalovirus infection in blood donors.
作者信息
Diosi P, Moldovan E, Tomescu N
出版信息
Br Med J. 1969 Dec 13;4(5684):660-2. doi: 10.1136/bmj.4.5684.660.
Abstract
Twenty-one out of 32 apparently healthy blood donors aged 21 to 65 years yielded positive complement fixation tests with a cytomegalovirus antigen, at titres ranging from 1:8 to 1:64. Virus was present in leucocyte cultures of fresh peripheral blood of two seropositive subjects from a total of 35 donors examined. Plasma and 48-hour stored blood specimens failed to disclose virus in culture. Viruria could not be demonstrated, and there was no evidence of recent illness in the study group. These findings suggest that subclinical viraemia is not uncommon in blood donors.
摘要
在32名年龄在21至65岁之间看似健康的献血者中，有21人对巨细胞病毒抗原的补体结合试验呈阳性，滴度范围为1:8至1:64。在总共35名接受检测的献血者中，两名血清反应阳性者的新鲜外周血白细胞培养物中发现了病毒。血浆和储存48小时的血液标本在培养中未发现病毒。未证实有病毒尿，且研究组中没有近期患病的证据。这些发现表明，亚临床病毒血症在献血者中并不罕见。
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