Suppr超能文献

与巨细胞病毒感染相关的冷反应性抗“i”抗体所致的严重溶血性贫血。

Severe haemolytic anaemia due to cold anti-'i' antibodies associated with cytomegalovirus infection.

作者信息

Aguado J M, Castrillo J M, Sanz J, Serrano J

机构信息

Department of Internal Medicine, Fundación Jiménez Díaz, Madrid, Spain.

出版信息

Postgrad Med J. 1990 May;66(775):392-4. doi: 10.1136/pgmj.66.775.392.

DOI:10.1136/pgmj.66.775.392
PMID:2164663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2426850/
Abstract

A 66 year old patient with multiple myeloma and monoclonal cryoglobulinaemia who developed a severe haemolytic anaemia following a cytomegalovirus infection is reported. The presence of a high titre of anti-'i' cold antibody of IgM subclass is demonstrated. Anti-'i' antibody disappeared when complement-fixation antibody titres against cytomegalovirus decreased. Various pathogenetic mechanisms involved in the development of haemolytic anaemia associated with cytomegalovirus infection are discussed. To our knowledge, this is the first case described in the English language publications associating severe haemolytic anaemia with an anti-'i' antibody after a cytomegalovirus infection in an immunocompromised patient.

摘要

报告了一名66岁患有多发性骨髓瘤和单克隆冷球蛋白血症的患者，其在巨细胞病毒感染后发生了严重的溶血性贫血。证实存在高滴度的IgM亚类抗“i”冷抗体。当针对巨细胞病毒的补体结合抗体滴度降低时，抗“i”抗体消失。讨论了与巨细胞病毒感染相关的溶血性贫血发生过程中涉及的各种发病机制。据我们所知，这是英文出版物中描述的首例免疫功能低下患者在巨细胞病毒感染后出现严重溶血性贫血并伴有抗“i”抗体的病例。

相似文献

1
Severe haemolytic anaemia due to cold anti-'i' antibodies associated with cytomegalovirus infection.与巨细胞病毒感染相关的冷反应性抗“i”抗体所致的严重溶血性贫血。
Postgrad Med J. 1990 May;66(775):392-4. doi: 10.1136/pgmj.66.775.392.
2
Response to intravenous immunoglobulin G in an infant with immunoglobulin A-associated autoimmune haemolytic anaemia.一名患有免疫球蛋白A相关自身免疫性溶血性贫血婴儿对静脉注射免疫球蛋白G的反应。
Vox Sang. 2004 Feb;86(2):151-3. doi: 10.1111/j.0042-9007.2004.00392.x.
3
Cytomegalovirus-induced haemolytic anaemia after cardiac surgery.心脏手术后巨细胞病毒诱导的溶血性贫血
Thorax. 1976 Dec;31(6):786-8. doi: 10.1136/thx.31.6.786.
4
Immunoblastic lymphoma of the colon in a renal transplant patient presenting with autoimmune haemolytic anaemia of the cold antibody type.一名肾移植患者出现冷抗体型自身免疫性溶血性贫血，同时患有结肠免疫母细胞淋巴瘤。
Nephrol Dial Transplant. 1997 Sep;12(9):2000-1. doi: 10.1093/ndt/12.9.2000.
5
Autoimmune haemolytic anaemia associated with low-titre anti-i cold agglutinins in a Nigerian. A case report.一名尼日利亚人患与低滴度抗 -i冷凝集素相关的自身免疫性溶血性贫血。病例报告。
Afr J Med Med Sci. 1991 Mar;20(1):1-4.
6
Mixed-type autoimmune haemolytic anaemia: unusual cases and a case associated with splenic T-cell angioimmunoblastic non-Hodgkin's lymphoma.混合型自身免疫性溶血性贫血：罕见病例及一例与脾 T 细胞血管免疫母细胞性非霍奇金淋巴瘤相关的病例
Hematology. 2007 Apr;12(2):159-62. doi: 10.1080/110245330601111466.
7
IgM anti-D as auto-antibody in a case of 'cold' auto-immune haemolytic anaemia.
Vox Sang. 1988;54(3):174-6. doi: 10.1111/j.1423-0410.1988.tb03895.x.
8
[Mixed warm and cold antibody-type autoimmune hemolytic anemia in a healthy pregnant woman with primary cytomegalovirus infection].
Rinsho Ketsueki. 2002 Jan;43(1):29-34.
9
[IgA-mediated auto-immune haemolytic anaemia revealing a hepatitis C virus infection].[IgA介导的自身免疫性溶血性贫血揭示丙型肝炎病毒感染]
Rev Med Interne. 2008 Feb;29(2):135-8. doi: 10.1016/j.revmed.2007.08.009. Epub 2007 Sep 21.
10
Warm IgM anti-IT causing autoimmune haemolytic anaemia.
Vox Sang. 1977;32(3):135-42. doi: 10.1111/j.1423-0410.1977.tb00618.x.

引用本文的文献

1
A Case of Multiple Myeloma Presenting with Gastrointestinal Bleeding and Evans Syndrome.一例以胃肠道出血和伊文氏综合征为表现的多发性骨髓瘤病例。
Cureus. 2019 Oct 22;11(10):e5969. doi: 10.7759/cureus.5969.

本文引用的文献

1
INFECTIOUS MONONUCLEOSIS: AN UNSUSPECTED SOURCE ON ANTI-I.传染性单核细胞增多症：抗-I的一个意想不到的来源
Br J Haematol. 1965 Jul;11:480-3. doi: 10.1111/j.1365-2141.1965.tb06611.x.
2
Syndromes of cytomegalovirus infection.巨细胞病毒感染综合征
Adv Intern Med. 1980;26:447-66.
3
Immunologic abnormalities induced by postperfusion cytomegalovirus infection.灌注后巨细胞病毒感染诱导的免疫异常。
Ann Intern Med. 1970 Oct;73(4):553-8. doi: 10.7326/0003-4819-73-4-553.
4
Cytomegalic inclusion-body disease associated with acquired autoimmune haemolytic anaemia.巨细胞包涵体病合并获得性自身免疫性溶血性贫血
Br Med J. 1968 Jun 22;2(5607):743-4. doi: 10.1136/bmj.2.5607.743.
5
Etiology and pathogenesis of acquired hemolytic anemia.
Transfusion. 1966 Sep-Oct;6(5):438-61. doi: 10.1111/j.1537-2995.1966.tb04759.x.
6
Cytomegalovirus hepatitis in the adult.
Lancet. 1967 Jun 24;1(7504):1351-4. doi: 10.1016/s0140-6736(67)91762-x.
7
A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival.一种多发性骨髓瘤的临床分期系统。测量的骨髓瘤细胞量与初始临床特征、治疗反应及生存情况的相关性。
Cancer. 1975 Sep;36(3):842-54. doi: 10.1002/1097-0142(197509)36:3<842::aid-cncr2820360303>3.0.co;2-u.
8
Improved survival times in multiple myeloma treated with melphalan, prednisone, cyclophosphamide, vincristine and BCNU: M-2 protocol.使用美法仑、泼尼松、环磷酰胺、长春新碱和卡莫司汀治疗多发性骨髓瘤的生存时间改善：M - 2方案
Am J Med. 1977 Dec;63(6):897-903. doi: 10.1016/0002-9343(77)90543-5.
9
Diseases produced by cytomegaloviruses.巨细胞病毒引起的疾病。
Med Clin North Am. 1978 Sep;62(5):1021-35. doi: 10.1016/s0025-7125(16)31752-7.
10
Anti-"i" antibody and hemolytic anemia associated with spontaneous cytomegalovirus mononucleosis.抗“i”抗体与自发性巨细胞病毒单核细胞增多症相关的溶血性贫血。
Am J Clin Pathol. 1977 May;67(5):459-61. doi: 10.1093/ajcp/67.5.459.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验