Rohde Paul, Ichikawa Laura, Simon Gregory E, Ludman Evette J, Linde Jennifer A, Jeffery Robert W, Operskalski Belinda H
Oregon Research Institute, 1715 Franklin Boulevard, Eugene, OR 97403-1983, USA.
Child Abuse Negl. 2008 Sep;32(9):878-87. doi: 10.1016/j.chiabu.2007.11.004. Epub 2008 Oct 22.
Examine whether (1) childhood maltreatment is associated with subsequent obesity and depression in middle-age; (2) maltreatment explains the associations between obesity and depression; and (3) binge eating or body dissatisfaction mediate associations between childhood maltreatment and subsequent obesity.
Data were obtained through a population-based survey of 4641 women (mean age=52 years) enrolled in a large health plan in the Pacific Northwest. A telephone survey assessed child sexual and physical abuse, obesity (BMI>or=30), depressive symptoms, binge eating, and body dissatisfaction. Data were analyzed using logistic regression models incorporating sampling weights.
Both child sexual and physical abuse were associated with a doubling of the odds of both obesity and depression, although child physical abuse was not associated with depression for the African American/Hispanic/American Indian subgroup. The association between obesity and depression (unadjusted OR=2.82; 95% CI=2.20-3.62) was reduced somewhat after controlling for sexual abuse (adjusted OR=2.54; 1.96-3.29) and for physical abuse (adjusted OR=2.63; 2.03-3.42). Controlling for potential mediators failed to substantially attenuate associations between childhood maltreatment and obesity.
This study is the first to our knowledge that compares associations of child abuse with both depression and obesity in adults. Although the study is limited by its cross-sectional design and brief assessments, the fact that child abuse predicted two debilitating conditions in middle-aged women indicates the potential long-term consequences of these experiences.
探究(1)童年期受虐是否与中年期随后出现的肥胖和抑郁相关;(2)受虐是否能解释肥胖与抑郁之间的关联;以及(3)暴饮暴食或身体不满是否介导童年期受虐与随后肥胖之间的关联。
数据通过对太平洋西北部一个大型健康计划中登记的4641名女性(平均年龄 = 52岁)进行的基于人群的调查获得。一项电话调查评估了儿童期性虐待和身体虐待、肥胖(BMI≥30)、抑郁症状、暴饮暴食和身体不满。使用纳入抽样权重的逻辑回归模型对数据进行分析。
儿童期性虐待和身体虐待均与肥胖和抑郁的几率翻倍相关,尽管对于非裔美国人/西班牙裔/美洲印第安人群体,儿童期身体虐待与抑郁无关。在控制了性虐待(调整后的比值比 = 2.54;95%可信区间 = 1.96 - 3.29)和身体虐待(调整后的比值比 = 2.63;2.03 - 3.42)后,肥胖与抑郁之间的关联(未调整的比值比 = 2.82;95%可信区间 = 2.20 - 3.62)有所降低。控制潜在中介因素未能显著减弱童年期受虐与肥胖之间的关联。
据我们所知,本研究首次比较了儿童期虐待与成年人抑郁和肥胖的关联。尽管该研究受限于其横断面设计和简短评估,但儿童期虐待能预测中年女性的两种衰弱状况这一事实表明了这些经历可能产生的长期后果。