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青少年偏执型精神分裂症。

Paranoid schizophrenia in adolescence.

作者信息

Apter A, Spivak B, Weizman A, Tyano S, Orvaschel H

机构信息

Gehah Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Israel.

出版信息

J Clin Psychiatry. 1991 Sep;52(9):365-8.

PMID:1894588
Abstract

BACKGROUND

Paranoid schizophrenia is considered to be a rare condition in adolescence. Since this is contrary to the authors' clinical experience, they hypothesized that a controlled study would show that a significant number of adolescents would be diagnosed with paranoid schizophrenia and that scores from the childhood version of the Schedule for Affective Disorders and Schizophrenia (K-SADS) would differentiate between the paranoid schizophrenic adolescents and adolescents with other types of schizophrenia or with affective disorder.

METHOD

The authors conducted a prospective study of 120 adolescents admitted consecutively to an adolescent psychiatric inpatient department. Patients were diagnosed on the basis of DSM-III after an 8-week period during which they were evaluated with a structured psychiatric history and psychiatric examination, the K-SADS, repeated nonstructured interviews, and extensive ward observations.

RESULTS

Thirty-eight percent of the schizophrenic adolescents and 14% of the total hospitalized population met the DSM-III criteria for paranoid schizophrenia. The symptom profile of the paranoid schizophrenic adolescents clearly distinguished them from adolescents with other psychiatric disorders.

CONCLUSIONS

Given the incidence of paranoid schizophrenia in an adolescent population, adolescent psychiatrists are likely to encounter this disorder. DSM-III-R should be used in future studies to further clarify the issue of the prevalence of paranoid schizophrenia in adolescents.

摘要

背景

偏执型精神分裂症在青少年中被认为是一种罕见病症。鉴于这与作者的临床经验相悖,他们推测一项对照研究将会表明,大量青少年会被诊断为偏执型精神分裂症,并且情感障碍和精神分裂症量表(K-SADS)儿童版的得分能够区分偏执型精神分裂症青少年与患有其他类型精神分裂症或情感障碍的青少年。

方法

作者对连续入住一家青少年精神科住院部的120名青少年进行了一项前瞻性研究。在为期8周的时间里,通过结构化精神病史和精神检查、K-SADS、反复的非结构化访谈以及广泛的病房观察对患者进行评估,之后依据《精神疾病诊断与统计手册》第三版(DSM-III)对患者作出诊断。

结果

38%的精神分裂症青少年以及14%的全部住院患者符合偏执型精神分裂症的DSM-III标准。偏执型精神分裂症青少年的症状特征明显将他们与患有其他精神疾病的青少年区分开来。

结论

鉴于偏执型精神分裂症在青少年人群中的发病率,青少年精神科医生很可能会遇到这种病症。未来的研究应使用《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)来进一步阐明青少年中偏执型精神分裂症患病率的问题。

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