Myers W C, Burket R C, Otto T A
Department of Psychiatry, University of Florida, Gainesville.
J Clin Psychiatry. 1993 Jan;54(1):21-6.
The purpose of this study was to investigate the differences between DSM-III-R Axis I and II psychiatric diagnoses in hospitalized adolescents with and without conduct disorder. The spectrum of psychopathology associated with conduct disorder, especially personality disorder symptoms and diagnoses, remains largely unexplored.
Twenty-five inpatients were evaluated using the Diagnostic Interview for Children and Adolescents, Adolescent Version (DICA-R-A); the Schedule for Affective Disorders and Schizophrenia for School-Age Children, Epidemiologic Version (K-SADS-E) (panic disorder and agoraphobia only); and the Structured Interview for DSM-III-R Personality Disorders (SIDP-R).
Fifty-two percent met criteria for conduct disorder, and the majority of these had comorbid substance abuse, attention-deficit hyperactivity disorder, and major depression. The diagnosis of conduct disorder was also associated with fulfilling criteria for multiple Axis II personality disorders, particularly passive aggressive and histrionic. Nearly three personality disorders per subject were found in those with conduct disorder, while those without conduct disorder averaged just over one personality disorder. There was a trend for female subjects with conduct disorders to have more frequent and varied personality disorder diagnoses. For the entire sample, males were significantly more likely to have conduct disorder, and females were significantly more likely to have borderline personality disorder.
These findings support conduct disorder as a multifaceted illness composed of diverse Axis I and II characteristics. Long-term follow-up studies are needed to determine the outcome of personality disorder diagnoses made in adolescents with and without conduct disorder.
本研究旨在调查患有和未患有品行障碍的住院青少年在DSM-III-R轴I和轴II精神疾病诊断方面的差异。与品行障碍相关的精神病理学范围,尤其是人格障碍症状和诊断,在很大程度上仍未得到探索。
使用儿童和青少年诊断访谈青少年版(DICA-R-A)、学龄儿童情感障碍和精神分裂症量表流行病学版(K-SADS-E)(仅用于惊恐障碍和广场恐惧症)以及DSM-III-R人格障碍结构化访谈(SIDP-R)对25名住院患者进行评估。
52%的患者符合品行障碍标准,其中大多数伴有物质滥用、注意力缺陷多动障碍和重度抑郁症。品行障碍的诊断还与符合多种轴II人格障碍标准相关,尤其是被动攻击型和表演型。患有品行障碍的患者平均每人有近三种人格障碍,而未患有品行障碍的患者平均每人只有一种多一点的人格障碍。患有品行障碍的女性患者有更频繁和多样的人格障碍诊断倾向。在整个样本中,男性患品行障碍的可能性显著更高,而女性患边缘型人格障碍的可能性显著更高。
这些发现支持将品行障碍视为一种由不同的轴I和轴II特征组成的多方面疾病。需要进行长期随访研究以确定患有和未患有品行障碍的青少年人格障碍诊断的结果。