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大疱性丹毒:并非罕见病症。

Blistering erysipelas: not a rare entity.

作者信息

Chong F Y, Thirumoorthy T

机构信息

Dermatology Unit, Singapore General Hospital, Outram Road, Singapore 169608.

出版信息

Singapore Med J. 2008 Oct;49(10):809-13.

Abstract

INTRODUCTION

Soft tissue infections are common, but erysipelas, especially its blistering feature, is an under-recognised entity. There have been few reports of blistering erysipelas. We aim to describe the clinical characteristics, management and the risk factors for erysipelas in 20 patients admitted in a tertiary hospital in Singapore.

METHODS

A chart review of all cases of erysipelas, diagnosed by experienced dermatologists and admitted to the Singapore General Hospital during the period January 2006 to August 2006, was conducted.

RESULTS

There were 20 patients (11 male, nine female) with an average age of 62.2 (range 31-86) years. The most commonly-involved site was the leg (75 percent), followed by the arm (15 percent) and face (ten percent). The clinical characteristics were well dermarcated (50 percent), erythema (100 percent) and oedema (85 percent), and bullae and vesicles formation (80 percent). Most presented with no pain (40 percent) and minimal signs of systemic toxicity. There was no positive blood culture, but the swab on the blistering erysipelas yielded positive cultures in 67 percent. The most common predisposing factor was disruption in the skin barrier (65 percent), followed by venous insufficiency (20 percent) and lymphoedema (25 percent). All patients received empirical antibiotics, most commonly penicillin and cloxacillin (65 percent), for an average duration of 20.65 (10-41) days, and with local care, there was complete resolution.

CONCLUSION

In our experience, erysipelas is a clinically distinct entity and commonly presents with bullae or vesicles. It has favourable prognosis, and rarely develops any complication with timely and appropriate therapy.

摘要

引言

软组织感染很常见,但丹毒,尤其是其水疱形成的特征,是一种未得到充分认识的病症。关于水疱性丹毒的报道很少。我们旨在描述新加坡一家三级医院收治的20例丹毒患者的临床特征、治疗及危险因素。

方法

对2006年1月至2006年8月期间由经验丰富的皮肤科医生诊断并入住新加坡总医院的所有丹毒病例进行病历回顾。

结果

共有20例患者(11例男性,9例女性),平均年龄62.2岁(范围31 - 86岁)。最常受累部位是腿部(75%),其次是手臂(15%)和面部(10%)。临床特征为边界清晰(50%)、红斑(100%)、水肿(85%)以及水疱和大疱形成(80%)。大多数患者无疼痛(40%)且全身毒性体征轻微。血培养均为阴性,但水疱性丹毒的拭子培养67%呈阳性。最常见的诱发因素是皮肤屏障破坏(65%),其次是静脉功能不全(20%)和淋巴水肿(25%)。所有患者均接受经验性抗生素治疗,最常用的是青霉素和氯唑西林(65%),平均疗程为20.65天(10 - 41天),经局部护理后均完全痊愈。

结论

根据我们的经验,丹毒是一种临床特征明显的病症,常表现为水疱或大疱。其预后良好,及时恰当治疗很少发生并发症。

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