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[憩室病的现代治疗]

[Modern therapy of diverticular disease].

作者信息

Leifeld L, Kruis W

机构信息

Abteilung für Innere Medizin, Evangelisches Krankenhaus Kalk, Köln, Deutschland.

出版信息

Internist (Berl). 2008 Dec;49(12):1415-6, 1418-20. doi: 10.1007/s00108-008-2150-8.

DOI:10.1007/s00108-008-2150-8
PMID:18946642
Abstract

New concepts are developed in the therapy of diverticular disease. 5-aminosalicylates can be administered in patients with slight forms of diverticulitis. In moderate diverticulitis antibiotics should be applied alternatively or additionally. In cases of severe diverticulitis patients should be kept fasting with parenteral nutrition and intravenous broad spectrum antibiotics. Small abscesses can be treated conservatively while abscesses larger than 4 cm should be drained in a first step and than treated surgically. A free perforation is still an absolute indication for emergency operation. In recurring diverticulitis indication for resection of the affected segment of the bowel should be considered depending on the extent of former attacks.

摘要

憩室病的治疗出现了新的理念。轻度憩室炎患者可使用5-氨基水杨酸酯。中度憩室炎患者应交替或额外使用抗生素。重度憩室炎患者应禁食并接受肠外营养及静脉注射广谱抗生素治疗。小脓肿可保守治疗,而直径大于4厘米的脓肿应首先进行引流,然后再进行手术治疗。游离穿孔仍然是急诊手术的绝对指征。对于复发性憩室炎,应根据既往发作的程度考虑是否切除受累肠段。

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Internist (Berl). 2008 Dec;49(12):1415-6, 1418-20. doi: 10.1007/s00108-008-2150-8.
2
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本文引用的文献

1
Incidence of perforated diverticulitis and risk factors for death in a UK population.英国人群中穿孔性憩室炎的发病率及死亡风险因素
Br J Surg. 2008 Jul;95(7):876-81. doi: 10.1002/bjs.6226.
2
Role of colonoscopy in patients with persistent acute diverticulitis.结肠镜检查在持续性急性憩室炎患者中的作用。
World J Gastroenterol. 2008 May 7;14(17):2763-6. doi: 10.3748/wjg.14.2763.
3
Clinical practice. Diverticulitis.临床实践。憩室炎。
N Engl J Med. 2007 Nov 15;357(20):2057-66. doi: 10.1056/NEJMcp073228.
4
Comparison of outcomes following ileostomy versus colostomy for defunctioning colorectal anastomoses.回肠造口术与结肠造口术用于结直肠吻合口减压的效果比较。
World J Surg. 2007 May;31(5):1142-51. doi: 10.1007/s00268-006-0218-y.
5
Continuous versus cyclic mesalazine therapy for patients affected by recurrent symptomatic uncomplicated diverticular disease of the colon.对于患有复发性症状性单纯性结肠憩室病的患者,持续与周期性美沙拉嗪治疗的对比研究
Dig Dis Sci. 2007 Mar;52(3):671-4. doi: 10.1007/s10620-006-9551-0.
6
Conservative treatment of acute colonic diverticulitis: are antibiotics always mandatory?急性结肠憩室炎的保守治疗:抗生素总是必需的吗?
Scand J Gastroenterol. 2007 Jan;42(1):41-7. doi: 10.1080/00365520600780650.
7
[Aminosalicylates and steroids in the treatment ot chronic inflammatory bowel diseases--consensus paper of the Working Group for Chronic Inflammatory Bowel Diseases of the OGGH].[氨基水杨酸类药物和类固醇药物治疗慢性炎症性肠病——奥地利胃肠病学会慢性炎症性肠病工作组共识文件]
Z Gastroenterol. 2006 Jun;44(6):525-38; discussion 539. doi: 10.1055/s-2006-926796.
8
Diverticulitis: a progressive disease? Do multiple recurrences predict less favorable outcomes?憩室炎:一种进行性疾病?多次复发是否预示着预后较差?
Ann Surg. 2006 Jun;243(6):876-830; discussion 880-3. doi: 10.1097/01.sla.0000219682.98158.11.
9
Practice parameters for sigmoid diverticulitis.乙状结肠憩室炎的诊疗规范。
Dis Colon Rectum. 2006 Jul;49(7):939-44. doi: 10.1007/s10350-006-0578-2.
10
[Mysterious lower gastrointestinal bleeding in diverticular disease of the colon].[结肠憩室病中的神秘下消化道出血]
Dtsch Med Wochenschr. 2005 Aug 26;130(34-35):1948-50. doi: 10.1055/s-2005-872608.