Fomenko G I, Shushevich S I, Khalmuradov A G
Ukr Biokhim Zh. 1976;48(6):701-5.
A reverse interrelation is established between the content of NAD and DNA in the chickens liver at different stages of ontogenetic development, especially pronounced at the stages of embryogenesis. The content of NAD which is the least in the liver of the 8-day embryos increases with development of chickens and reaches the maximum level by the 6-month age. The content of DNA is maximum in the embryonal period. The activity of NAD-pyrophosphorylase in the liver nuclei has the low value at early periods of the embryonal life and rises with development of organism, reaching the constant values in one-, two- and 6-month chickens. Judging by the curve of the NAD-glycohydrolase activity in the liver nuclei, the hydrolase breakdown of NAD occurs only after chickens hatching.
在个体发育的不同阶段,鸡肝脏中NAD(烟酰胺腺嘌呤二核苷酸)和DNA的含量之间建立了一种反向相互关系,在胚胎发生阶段尤为明显。8日龄胚胎肝脏中NAD含量最少,随着鸡的发育而增加,到6月龄时达到最高水平。DNA含量在胚胎期最高。肝细胞核中NAD-焦磷酸化酶的活性在胚胎生命早期较低,随着机体发育而升高,在1月龄、2月龄和6月龄鸡中达到恒定值。从肝细胞核中NAD-糖苷水解酶活性曲线判断,NAD的水解酶分解仅在雏鸡孵化后发生。