Pourabolghasem S, Najmi S, Arami M A
Department of Obstetrics and Gynecology, Tabriz University (Medical Sciences), Taleghani Hospital, Tabriz, Iran.
Eur Neurol. 2009;61(1):42-5. doi: 10.1159/000165349. Epub 2008 Oct 24.
To evaluate the role of some sex hormones in migraine headaches, the aim of this study was to assess the prevalence and characteristics of headache, especially migraine, in patients with polycystic ovary syndrome (PCO) compared with women without this disease.
One hundred and thirty-three women with PCO and 107 controls were interviewed by 2 neurologists experienced in headache diagnosis. The headache disorders were classified according to the International Headache Society criteria. The statistical significance was determined using the chi(2) test, and a p value of <0.05 was considered significant.
Forty-five women (33.8%) of the 133 cases without PCO complained of headache. Of the PCO patients, 48 women (44.9%) suffered from headache. The prevalence of headache was not significantly higher among women with PCO (p = 0.85). The same results were found for migraine headache (p = 0.13).
Migraine is not more frequent in women with PCO. It was concluded that male sex hormones and especially testosterone do not play an important role in the exacerbation of migraine headache.
为评估某些性激素在偏头痛中的作用，本研究旨在评估多囊卵巢综合征（PCO）患者与无此病女性相比头痛，尤其是偏头痛的患病率及特征。
由2名有头痛诊断经验的神经科医生对133例PCO女性和107例对照进行访谈。头痛障碍根据国际头痛协会标准分类。采用卡方检验确定统计学意义，p值<0.05被认为具有显著性。
133例无PCO的病例中有45例女性（33.8%）主诉头痛。在PCO患者中，48例女性（44.9%）患有头痛。PCO女性中头痛的患病率无显著更高（p = 0.85）。偏头痛的结果相同（p = 0.13）。
PCO女性中偏头痛并不更常见。得出的结论是，雄性激素尤其是睾酮在偏头痛加重中不发挥重要作用。
