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Genetical genomics: spotlight on QTL hotspots.

作者信息

Breitling Rainer, Li Yang, Tesson Bruno M, Fu Jingyuan, Wu Chunlei, Wiltshire Tim, Gerrits Alice, Bystrykh Leonid V, de Haan Gerald, Su Andrew I, Jansen Ritsert C

机构信息

Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, Haren, The Netherlands.

出版信息

PLoS Genet. 2008 Oct;4(10):e1000232. doi: 10.1371/journal.pgen.1000232. Epub 2008 Oct 24.

DOI:10.1371/journal.pgen.1000232
PMID:18949031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2563687/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a19/2563687/26f81023f38c/pgen.1000232.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a19/2563687/26f81023f38c/pgen.1000232.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a19/2563687/26f81023f38c/pgen.1000232.g001.jpg

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Nat Genet. 2008 Jul;40(7):854-61. doi: 10.1038/ng.167. Epub 2008 Jun 15.
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Common and rare variants in multifactorial susceptibility to common diseases.常见疾病多因素易感性中的常见和罕见变异。
利用单核苷酸多态性(SNP)和等位基因特异性表达数据在SNP扰动下学习基因网络。
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Network reconstruction for trans acting genetic loci using multi-omics data and prior information.利用多组学数据和先验信息进行转录遗传基因座的网络重建。
Genome Med. 2022 Nov 7;14(1):125. doi: 10.1186/s13073-022-01124-9.
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Prioritizing candidate eQTL causal genes in Arabidopsis using RANDOM FORESTS.利用随机森林优先选择拟南芥中的候选 eQTL 因果基因。
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A consensus map for quality traits in durum wheat based on genome-wide association studies and detection of ortho-meta QTL across cereal species.基于全基因组关联研究和跨谷类物种直系-间源QTL检测的硬粒小麦品质性状共识图谱。
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