Hutchinson Amanda D, Mathias J L, Jacobson B L, Ruzic L, Bond A N, Banich Marie T
School of Psychology, University of Adelaide, Adelaide, SA, Australia.
Exp Brain Res. 2009 Jan;192(3):455-64. doi: 10.1007/s00221-008-1604-5. Epub 2008 Oct 24.
We investigated the relationship between the morphology of the corpus callosum (CC) and IQ in a healthy sample of individuals in their late teens and early twenties. The relationship between the area of the CC, measured at the midline, and IQ showed regional differences. We observed that a higher estimated performance IQ was associated with smaller area in the posterior regions of the CC, a finding that differs from a positive association previously observed in a somewhat older adult sample. In contrast, higher estimated verbal IQ was associated with decreased fractional anisotropy of the genu, an anterior portion of the CC. Age effects were also observed such that older age was associated with larger CC area. Our results suggest that CC morphology is related to cognitive performance, which may have implications for clinical populations in whom CC morphology is atypical.
我们在一组年龄在十八九岁和二十出头的健康个体样本中，研究了胼胝体（CC）形态与智商之间的关系。在中线测量的CC面积与智商之间的关系呈现出区域差异。我们观察到，较高的估计操作智商与CC后部区域较小的面积相关，这一发现与之前在年龄稍大的成人样本中观察到的正相关有所不同。相比之下，较高的估计语言智商与CC前部膝部的分数各向异性降低相关。还观察到了年龄效应，即年龄越大，CC面积越大。我们的结果表明，CC形态与认知表现有关，这可能对CC形态不典型的临床人群具有启示意义。
