Tucker Gregory, Robards Kevin
School of Biosciences, University of Nottingham, Loughborough, Leics, UK.
Crit Rev Food Sci Nutr. 2008 Nov;48(10):929-66. doi: 10.1080/10408390701761977.
Biophenols and their associated activity have generated intense interest. Current topics of debate are their bioavailability and bioactivity. It is generally assumed that their plasma concentrations are insufficient to produce the health benefits previously attributed to their consumption. However, data on localized in vivo concentrations are not available and many questions remain unanswered. Potential mechanisms by which they may exert significant bioactivity are discussed together with structure activity relationships. Biophenols are highly reactive species and they can react with a range of other compounds. Products of their reaction when functioning as antioxidants are examined.
生物酚及其相关活性引起了人们的浓厚兴趣。当前争论的话题是它们的生物利用度和生物活性。人们普遍认为，它们在血浆中的浓度不足以产生先前归因于其摄入的健康益处。然而，关于体内局部浓度的数据并不存在，许多问题仍未得到解答。本文讨论了它们可能发挥显著生物活性的潜在机制以及构效关系。生物酚是高反应性物质，它们可以与一系列其他化合物发生反应。研究了它们作为抗氧化剂时的反应产物。
