Mukai T, Yasuoka S, Terashi H, Tsubota N
Department of Surgery, Rokkou Hospital, Kobe, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1991 Jun;39(6):956-61.
A 21-year-old male was admitted with SVC syndrome. Chest X-ray film showed an abnormal density on the upper mediastinum, that was recognized thymoma on the needle aspiration specimen. The large tumor, which extensively infiltrated the surrounding tissues (SVC, the right brachiocephalic vein, bilateral lungs and the pericardium) led us to choose preoperative chemotherapy. CDDP (cisdiammin-edichloroplatinum) was infused through the right IMA (internal mammary artery). After obtaining the major response the tumor mass was resected with adjacent structure accompised vessels reconstructions. Histological examination revealed totally necrosed tissue. Three years after initiation of therapy, the patient is doing well. The therapy with CDDP injection into selective IMA for invasive thymoma before operation was considered to be very useful utilized.
一名21岁男性因上腔静脉综合征入院。胸部X线片显示上纵隔密度异常，针吸标本确诊为胸腺瘤。巨大肿瘤广泛浸润周围组织（上腔静脉、右头臂静脉、双侧肺和心包），因此我们选择术前化疗。顺铂通过右乳内动脉注入。在取得主要缓解后，切除肿瘤块并进行相邻结构的血管重建。组织学检查显示组织完全坏死。治疗开始三年后，患者情况良好。术前经选择性乳内动脉注射顺铂治疗浸润性胸腺瘤被认为非常有效。
