Tanaka K, Murota Y, Ando T, Asano K, Yamaguchi T, Wada G
Department of Thoracic and Cardiovascular Surgery, JR Tokyo General Hospital, Japan.
Kyobu Geka. 1996 Sep;49(10):868-71.
A 25-year-old male patient of invasive thymoma was referred to our institute on March'95. He had night coughs and on the annual chest X ray exam a large tumor was found in antero-superior mediastinum. At first his tumor was too large to be resected and left brachiocephalic vein was completely occluded. By needle biopsy it was proved to be thymoma, therefore, preoperative chemotherapy was planned. The tumor responded well to the two courses of ADOC (ADM, CDDP, VCR, CAP) therapy and the tumor seemed to become resectable. In June operation was performed and the tumor was resected completely. It appears that in case of stage Ill invasive thymoma, preoperative chemotherapy is one of the choices although it seems unresectable.
一名25岁的侵袭性胸腺瘤男性患者于1995年3月转诊至我院。他有夜间咳嗽症状，在年度胸部X线检查中发现前上纵隔有一个大肿瘤。起初，他的肿瘤太大无法切除，左头臂静脉完全闭塞。经针吸活检证实为胸腺瘤，因此计划进行术前化疗。肿瘤对两疗程的ADOC（阿霉素、顺铂、长春新碱、环磷酰胺）治疗反应良好，肿瘤似乎变得可切除。6月进行了手术，肿瘤被完全切除。看来，对于Ⅲ期侵袭性胸腺瘤患者，尽管肿瘤似乎无法切除，但术前化疗是一种选择。
