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[骨质疏松性骨折的治疗。椎体成形术和后凸成形术的新方法]

[Treatment of osteoporotic fractures. A new approach by vertebroplasty and kyphoplasty].

作者信息

Fabeck L

机构信息

Service d'Orthopédie, Clinique du dos, C.H.U. Saint Pierre et Hôpital Erasme, Bruxelles.

出版信息

Rev Med Brux. 2008 Sep;29(4):317-22.

PMID:18949983
Abstract

Osteoporosis is a systemic disease and results in progressive bone mineral loss and concurrent change in bone architecture that leave bone vulnerable to fracture. In one third of patients with acute vertebral fracture, severe pain and limited mobility persist despite appropriate nonoperative management. Vertebroplasty is a minimally invasive method that involved the percutaneous injection of cement into a collapsed vertebral body to stabilize the fractured vertebra. The indication of this technique is a painful fracture after 8 weeks of conservative treatment. Contraindications include coagulopathy, absence of facilities to perform emergency decompressive surgery, a vertebral collapse greater than 65 % and a fracture of the vertebra posterior wall. The procedure results in quick, effective pain relief and complications as epidural leakage or thermal necrosis by cement extravasation are rare. Vertebroplasty does not expand the collapsed vertebra. Kyphoplasty is a modification of this first technique and offers potential advantages as lower risk of cement extravasation and better restoration of the vertebral body height. A cannula is introduced into the vertebral body via a transpedicular approach like for the vertebroplasty technique but it is followed by insertion of an inflatable bone tamp, which when deployed reduces partially the compression fracture. This then creates a cavity to be filled with bone cement. Considering the higher rates of morbidity or mortality that is associated with osteoporotic fractures, early mobilization in these patients is of prime importance and can be achieved by using each of this two techniques with a relative low complication rate.

摘要

骨质疏松症是一种全身性疾病,会导致进行性骨矿物质流失以及骨结构的同时改变,使骨骼易发生骨折。在三分之一的急性椎体骨折患者中,尽管进行了适当的非手术治疗,严重疼痛和活动受限仍会持续。椎体成形术是一种微创方法,涉及经皮将骨水泥注入塌陷的椎体以稳定骨折椎体。该技术的适应症是保守治疗8周后的疼痛性骨折。禁忌症包括凝血功能障碍、缺乏进行紧急减压手术的设备、椎体塌陷超过65%以及椎体后壁骨折。该手术能快速、有效地缓解疼痛,且诸如骨水泥外渗导致的硬膜外渗漏或热坏死等并发症很少见。椎体成形术不会使塌陷的椎体扩张。后凸成形术是对第一种技术的改良,具有骨水泥外渗风险较低和椎体高度恢复较好等潜在优势。通过与椎体成形术类似的经椎弓根入路将套管插入椎体,但随后要插入一个可膨胀的骨扩张器,其展开时可部分减轻压缩性骨折。这会形成一个用于填充骨水泥的空腔。考虑到骨质疏松性骨折相关的较高发病率或死亡率,这些患者的早期活动至关重要,并且通过使用这两种并发症发生率相对较低的技术均可实现。

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