• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

住院患者低尿酸血症的临床意义

Clinical significance of hypouricemia in hospitalized patients.

作者信息

Ogino K, Hisatome I, Saitoh M, Miyamoto J, Ishiko R, Hasegawa J, Kotake H, Mashiba H

机构信息

First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.

出版信息

J Med. 1991;22(2):76-82.

PMID:1895016
Abstract

Serum uric acid was measured in 586 normal subjects and 1,220 hospitalized patients. Hypouricemia was noted in 0.34% of the normal subjects and 2.54% of the hospitalized patients. Among hospitalized patients with hypouricemia, 22 were on medication, including allopurinol, anticancer drugs, antibiotics and glucocorticoids. Twenty-one patients had liver disorders and 11 of them had received transfusions. Neoplastic diseases were noted in 14 patients. Thus, hypouricemia was found to be relatively common in hospitalized patients, and seems to be caused mainly by medication, neoplastic diseases, liver disorders and transfusions.

摘要

对586名正常受试者和1220名住院患者进行了血清尿酸检测。正常受试者中低尿酸血症的发生率为0.34%,住院患者中为2.54%。在低尿酸血症的住院患者中,22人正在服用药物,包括别嘌醇、抗癌药物、抗生素和糖皮质激素。21名患者患有肝脏疾病,其中11人接受过输血。14名患者患有肿瘤疾病。因此,低尿酸血症在住院患者中相对常见,似乎主要由药物、肿瘤疾病、肝脏疾病和输血引起。

相似文献

1
Clinical significance of hypouricemia in hospitalized patients.住院患者低尿酸血症的临床意义
J Med. 1991;22(2):76-82.
2
[Prevalence, physiopathology and processes associated with hypouricemia in a hospitalized population: analysis of 27,987 analytic determinations].[住院患者低尿酸血症的患病率、生理病理学及相关过程:27987例分析测定结果分析]
Rev Clin Esp. 1990 Mar;186(5):211-5.
3
Frequency and causes of hypouricemia in hospital patients.住院患者低尿酸血症的发生率及病因
Isr J Med Sci. 1977 May;13(5):529-30.
4
Poor prognosis of patients with intra-abdominal sepsis and hypouricemia.腹内脓毒症合并低尿酸血症患者的预后较差。
Surg Gynecol Obstet. 1979 Mar;148(3):358-60.
5
Prevalence and possible causes of hypouricemia at a tertiary care hospital.一家三级护理医院低尿酸血症的患病率及可能病因
Korean J Intern Med. 2016 Sep;31(5):971-6. doi: 10.3904/kjim.2015.125. Epub 2016 Mar 9.
6
Hypouricemia and intravenous infusions.低尿酸血症与静脉输液
J Rheumatol. 1983 Feb;10(1):66-70.
7
Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level.通过降低血清尿酸水平的能力,使用别嘌醇来减缓肾脏疾病的进展。
Am J Kidney Dis. 2006 Jan;47(1):51-9. doi: 10.1053/j.ajkd.2005.10.006.
8
Renal tubular hypouricemia and calcium urolithiasis.肾小管性低尿酸血症与钙结石症
Scanning Microsc. 1993 Mar;7(1):417-21.
9
Trimethoprim-sulfamethoxazole and hypouricemia.甲氧苄啶-磺胺甲恶唑与低尿酸血症
Clin Nephrol. 1996 Sep;46(3):193-8.
10
Efficacy and safety of allopurinol in patients with hypoxanthine-guanine phosphoribosyltransferase deficiency.别嘌醇在次黄嘌呤-鸟嘌呤磷酸核糖转移酶缺乏患者中的疗效与安全性。
Metabolism. 2007 Sep;56(9):1179-86. doi: 10.1016/j.metabol.2007.04.013.

引用本文的文献

1
Drug-Induced Hypouricemia.药物性低尿酸血症
Drug Saf. 2025 Feb;48(2):129-142. doi: 10.1007/s40264-024-01485-7. Epub 2024 Sep 17.
2
Prediction for Risk of Hypouricemia in Hospitalized Patients: A Single-center, Retrospective Cohort Study.住院患者低尿酸血症风险预测:一项单中心回顾性队列研究
Intern Med. 2025 Apr 1;64(7):1009-1016. doi: 10.2169/internalmedicine.3517-24. Epub 2024 Sep 11.
3
Impact of Hyper- and Hypo-Uricemia on Kidney Function.高尿酸血症和低尿酸血症对肾功能的影响。
Biomedicines. 2023 Apr 24;11(5):1258. doi: 10.3390/biomedicines11051258.
4
Characterization of Urate Metabolism and Complications of Patients with Renal Hypouricemia.尿酸代谢特征及肾性低尿酸血症患者并发症分析。
Intern Med. 2023 Jul 1;62(13):1915-1920. doi: 10.2169/internalmedicine.0457-22. Epub 2022 Nov 23.
5
Evaluation of proximal tubule functions in children with COVID-19: a prospective analytical study.评价 COVID-19 患儿近端肾小管功能:一项前瞻性分析研究。
World J Pediatr. 2022 Sep;18(9):607-612. doi: 10.1007/s12519-022-00552-2. Epub 2022 May 4.
6
Xanthinuria Type 1 with a Novel Mutation in Xanthine Dehydrogenase and a Normal Endothelial Function.黄嘌呤尿症 1 型伴黄嘌呤氧化酶的新突变和正常的内皮功能。
Intern Med. 2022;61(9):1383-1386. doi: 10.2169/internalmedicine.7897-21. Epub 2022 May 1.
7
Hypouricemia and Urate Transporters.低尿酸血症与尿酸转运蛋白
Biomedicines. 2022 Mar 11;10(3):652. doi: 10.3390/biomedicines10030652.
8
Hypouricemia: what the practicing rheumatologist should know about this condition.低尿酸血症:风湿科医生应该了解的这种疾病。
Clin Rheumatol. 2020 Jan;39(1):135-147. doi: 10.1007/s10067-019-04788-8. Epub 2019 Oct 24.
9
A Point-based Mortality Prediction System for Older Adults with Diabetes.基于点的老年糖尿病患者死亡率预测系统。
Sci Rep. 2017 Oct 4;7(1):12652. doi: 10.1038/s41598-017-12751-3.
10
Prevalence and possible causes of hypouricemia at a tertiary care hospital.一家三级护理医院低尿酸血症的患病率及可能病因
Korean J Intern Med. 2016 Sep;31(5):971-6. doi: 10.3904/kjim.2015.125. Epub 2016 Mar 9.