Ogino K, Hisatome I, Saitoh M, Miyamoto J, Ishiko R, Hasegawa J, Kotake H, Mashiba H
First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
J Med. 1991;22(2):76-82.
Serum uric acid was measured in 586 normal subjects and 1,220 hospitalized patients. Hypouricemia was noted in 0.34% of the normal subjects and 2.54% of the hospitalized patients. Among hospitalized patients with hypouricemia, 22 were on medication, including allopurinol, anticancer drugs, antibiotics and glucocorticoids. Twenty-one patients had liver disorders and 11 of them had received transfusions. Neoplastic diseases were noted in 14 patients. Thus, hypouricemia was found to be relatively common in hospitalized patients, and seems to be caused mainly by medication, neoplastic diseases, liver disorders and transfusions.
对586名正常受试者和1220名住院患者进行了血清尿酸检测。正常受试者中低尿酸血症的发生率为0.34%,住院患者中为2.54%。在低尿酸血症的住院患者中,22人正在服用药物,包括别嘌醇、抗癌药物、抗生素和糖皮质激素。21名患者患有肝脏疾病,其中11人接受过输血。14名患者患有肿瘤疾病。因此,低尿酸血症在住院患者中相对常见,似乎主要由药物、肿瘤疾病、肝脏疾病和输血引起。