Ypenburg Claudia, Westenberg Jos J, Bleeker Gabe B, VAN de Veire Nico, Marsan Nina A, Henneman Maureen M, van der Wall Ernst E, Schalij Martin J, Abraham Theodore P, Barold S Serge, Bax Jeroen J
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
Pacing Clin Electrophysiol. 2008 Nov;31(11):1475-99. doi: 10.1111/j.1540-8159.2008.01212.x.
Cardiac resynchronization therapy (CRT) is an established therapy for patients with advanced heart failure, depressed left ventricular function, and wide QRS complex. However, individual response varies, and a substantial amount of patients do not respond to CRT. Recent studies observed that assessment of inter- and particularly intraventricular dyssynchrony may allow identification of potential responders to CRT. In addition, presence of scar tissue and venous anatomy may play a role in the selection of candidates. In this review, an extensive overview of the available dyssynchrony measurements is provided using echocardiography as well as magnetic resonance imaging (MRI) and nuclear imaging. Furthermore, other information derived from MRI, nuclear imaging, and computed tomography useful for the selection of potential candidates for CRT will be discussed.
心脏再同步治疗（CRT）是针对晚期心力衰竭、左心室功能减退和QRS波群增宽患者的一种既定治疗方法。然而，个体反应各不相同，相当一部分患者对CRT无反应。最近的研究观察到，评估心室间尤其是心室内不同步可能有助于识别CRT的潜在反应者。此外，瘢痕组织的存在和静脉解剖结构可能在候选者的选择中起作用。在本综述中，使用超声心动图以及磁共振成像（MRI）和核成像对可用的不同步测量方法进行了广泛概述。此外，还将讨论从MRI、核成像和计算机断层扫描中获得的有助于选择CRT潜在候选者的其他信息。
