Mackenzie I R, Gilbert J J
Department of Pathology, Victoria Hospital, London, Ontario, Canada.
J Neurol Neurosurg Psychiatry. 1991 Jul;54(7):572-5. doi: 10.1136/jnnp.54.7.572.
Five colloid cysts of the third ventricle were compared with two spinal enterogenous cysts to examine the hypothesis that these entities have the same origin from primitive endodermal tissue. All the lesions showed cuboidal and columnar epithelium with mucus containing goblet cells and cilia. Immunohistochemistry for cytokeratin, EMA and CEA was positive in all the colloid cyst and enterogenous cyst epithelium. S-100 was focally positive in three of the colloid and one of the enterogenous cysts while vimentin and GFAP were negative in both. The anatomical distribution of both colloid and enterogenous cysts is reviewed. An illustrative case of an identical cyst within the fourth ventricle is presented. This suggests that the similarities between colloid and enterogenous cysts and the presence of identical lesions along the neuroaxis indicate that these structures are derived from primitive foregut endoderm.
将第三脑室的五个胶样囊肿与两个脊髓肠源性囊肿进行比较，以检验这些实体源自原始内胚层组织这一假说。所有病变均显示为立方上皮和柱状上皮，伴有含杯状细胞和纤毛的黏液。细胞角蛋白、上皮膜抗原（EMA）和癌胚抗原（CEA）的免疫组化在所有胶样囊肿和肠源性囊肿上皮中均呈阳性。S-100在三个胶样囊肿和一个肠源性囊肿中呈局灶性阳性，而波形蛋白和胶质纤维酸性蛋白（GFAP）在两者中均为阴性。本文回顾了胶样囊肿和肠源性囊肿的解剖分布情况。还展示了一例第四脑室内相同囊肿的病例。这表明胶样囊肿和肠源性囊肿之间的相似性以及沿神经轴存在相同病变，提示这些结构源自原始前肠内胚层。
