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根治性前列腺切除术后生化复发后的挽救性放疗:加拿大泌尿生殖放射肿瘤学家共识会议纪要

Salvage radiotherapy following biochemical relapse after radical prostatectomy: proceedings of the Genito-Urinary Radiation Oncologists of Canada consensus meeting.

作者信息

Sia Michael, Pickles Tom, Morton Gerard, Souhami Louis, Lukka Himu, Warde Padraig

机构信息

Radiation Oncology Program, Tom Baker Cancer Centre, Calgary, Alta., the.

出版信息

Can Urol Assoc J. 2008 Oct;2(5):500-7. doi: 10.5489/cuaj.916.

DOI:10.5489/cuaj.916
PMID:18953445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2572238/
Abstract

For patients with recurrent prostate cancer after radical prostatectomy, salvage radiotherapy is the only potentially curative treatment option. However, until recently there has been a paucity of data on the effectiveness of this approach. In light of recently published studies, the Genito-Urinary Radiation Oncologists of Canada (GUROC) met and crafted a consensus statement regarding the current place of salvage radiotherapy. GUROC also identified gaps in current knowledge and identified ongoing study protocols that will advance our knowledge in this area.This report summarizes the main conclusions of the meeting and the commentary provided during the consensus-building process, and outlines the consensus statement that was subsequently adopted.

摘要

对于前列腺癌根治术后复发的患者,挽救性放疗是唯一可能治愈的治疗选择。然而,直到最近,关于这种治疗方法有效性的数据还很匮乏。鉴于最近发表的研究,加拿大泌尿生殖放射肿瘤学家(GUROC)召开会议并就挽救性放疗的当前地位制定了一份共识声明。GUROC还确定了当前知识方面的差距,并确定了正在进行的研究方案,这些方案将增进我们在这一领域的知识。本报告总结了会议的主要结论以及在共识形成过程中提供的评论,并概述了随后通过的共识声明。

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1
Salvage radiotherapy following biochemical relapse after radical prostatectomy: proceedings of the Genito-Urinary Radiation Oncologists of Canada consensus meeting.根治性前列腺切除术后生化复发后的挽救性放疗:加拿大泌尿生殖放射肿瘤学家共识会议纪要
Can Urol Assoc J. 2008 Oct;2(5):500-7. doi: 10.5489/cuaj.916.
2
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Can Urol Assoc J. 2008 Apr;2(2):95-9. doi: 10.5489/cuaj.467.
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Current topics in radiotherapy for genitourinary cancers: Consensus statements of the Genitourinary Radiation Oncologists of Canada.泌尿生殖系统癌症放射治疗的当前主题:加拿大泌尿生殖系统放射肿瘤学家的共识声明
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[Salvage radical prostatectomy].挽救性根治性前列腺切除术
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[Not Available].[无可用内容]
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本文引用的文献

1
Adjuvant radiotherapy following radical prostatectomy: Genito-Urinary Radiation Oncologists of Canada Consensus Statement.前列腺癌根治术后辅助放疗:加拿大泌尿生殖放射肿瘤学家共识声明
Can Urol Assoc J. 2008 Apr;2(2):95-9. doi: 10.5489/cuaj.467.
2
Anatomic boundaries of the clinical target volume (prostate bed) after radical prostatectomy.根治性前列腺切除术后临床靶区(前列腺床)的解剖边界。
Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1090-9. doi: 10.1016/j.ijrobp.2007.04.068.
3
Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy.预测前列腺癌根治术后复发性前列腺癌挽救性放射治疗的结果。
J Clin Oncol. 2007 May 20;25(15):2035-41. doi: 10.1200/JCO.2006.08.9607.
4
Endorectal MRI assessment of local relapse after surgery for prostate cancer: A model to define treatment field guidelines for adjuvant radiotherapy in patients at high risk for local failure.前列腺癌手术后局部复发的直肠内MRI评估:一种为局部失败高危患者辅助放疗定义治疗野指南的模型。
Int J Radiat Oncol Biol Phys. 2007 Feb 1;67(2):356-61. doi: 10.1016/j.ijrobp.2006.08.079.
5
Radiation rescue for biochemical failure after surgery for prostate cancer: predictive parameters and an assessment of contemporary predictive models.前列腺癌手术后生化复发的放射挽救治疗:预测参数及当代预测模型评估
Am J Clin Oncol. 2006 Oct;29(5):446-50. doi: 10.1097/01.coc.0000221237.58653.0e.
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Salvage radiotherapy for isolated prostate specific antigen increase after radical prostatectomy: evaluation of prognostic factors and creation of a prognostic scoring system.根治性前列腺切除术后孤立性前列腺特异性抗原升高的挽救性放疗:预后因素评估及预后评分系统的建立
J Urol. 2006 Sep;176(3):985-90. doi: 10.1016/j.juro.2006.04.083.
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Long-term salvage radiotherapy outcome after radical prostatectomy and relapse predictors.前列腺癌根治术后长期挽救性放疗的结果及复发预测因素
J Urol. 2005 Dec;174(6):2204-8, discussion 2208. doi: 10.1097/01.ju.0000181223.99576.ff.
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Salvage radiation therapy for prostate specific antigen progression following radical prostatectomy: 10-year outcome estimates.前列腺癌根治术后前列腺特异性抗原进展的挽救性放射治疗:10年预后评估
J Urol. 2005 Oct;174(4 Pt 1):1282-6. doi: 10.1097/01.ju.0000173911.82467.f9.
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Risk of prostate cancer-specific mortality following biochemical recurrence after radical prostatectomy.根治性前列腺切除术后生化复发后前列腺癌特异性死亡风险。
JAMA. 2005 Jul 27;294(4):433-9. doi: 10.1001/jama.294.4.433.
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The impact of surgical approach (nerve bundle preservation versus wide local excision) on surgical margins and biochemical recurrence following radical prostatectomy.手术方式(保留神经束与广泛局部切除)对根治性前列腺切除术后手术切缘及生化复发的影响。
J Urol. 2004 Oct;172(4 Pt 1):1328-32. doi: 10.1097/01.ju.0000138681.64035.dc.