Qu Hui, Wang Cheng-feng, Zhao Ping, Shan Yi, Zhao Dong-bing
Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhonghua Yi Xue Za Zhi. 2008 May 27;88(20):1405-7.
To evaluate the role of local resection in treatment of pancreatic neoplasms.
The clinical data of 17 patients with pancreatic neoplasms, 3 males and 14 females, aged 47.9 (34-67), who underwent local resection from January 1996 to June 2007 were analyzed.
Of the 17 tumors, 9 were located in the head, 7 located in the body, and 1 located in the tail of pancreas. The diameters of the 17 tumors were 1.5-8.0 cm, 3.6 cm on average, and the diameters of 8 tumors were above 4 cm. Pathological examination confirmed 8 tumors as nonfunctioning insulinoma, 5 as solid pseudopapillary tumor, 1 as neurilemmoma, 1 as cyst, 1 as gastrointestinal stroma tumor, and 1 as low-graded malignant tumor. Pancreatic leakage occurred in 7 cases (41.2%) and no death, recurrence, and endocrine and exocrine insufficiency occurred after operation.
Capable pf preserving endocrine and exocrine functions, local resection is a feasible method for benign or low-graded malignant pancreatic neoplasms, however, with a high rate of pancreatic leakage.
评估局部切除术在胰腺肿瘤治疗中的作用。
分析1996年1月至2007年6月期间接受局部切除术的17例胰腺肿瘤患者的临床资料,其中男性3例,女性14例,年龄47.9岁(34 - 67岁)。
17例肿瘤中,9例位于胰头,7例位于胰体,1例位于胰尾。17例肿瘤直径为1.5 - 8.0 cm,平均3.6 cm,8例肿瘤直径大于4 cm。病理检查证实8例为无功能性胰岛素瘤,5例为实性假乳头状瘤,1例为神经鞘瘤,1例为囊肿,1例为胃肠道间质瘤,1例为低级别恶性肿瘤。7例(41.2%)发生胰漏,术后无死亡、复发及内分泌和外分泌功能不全发生。
局部切除术能够保留内分泌和外分泌功能,是治疗良性或低级别恶性胰腺肿瘤的一种可行方法,然而,胰漏发生率较高。