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[低灌注性视网膜病变所致新生血管性青光眼的临床特征]

[Clinical features of hypoperfusion retinopathy induced neovascular glaucoma].

作者信息

Zhou Bi-ye, Zhang Mao-nian, Zhao Na, Wei Shi-hui

机构信息

Department of Ophthalmology, General Hospital of PLA, Beijing 100853, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2008 May;44(5):398-401.

Abstract

OBJECTIVE

To analyze the clinical features of hypoperfusion retinopathy induced neovascular glaucoma

METHODS

This retrospective case series included 18 cases (18 eyes) with hypoperfusion retinopathy induced neovascular glaucoma Among them, there were 15 male and 3 female; 10 right eye and 5 left eye. The average age was 40-year-old (ranged from 18- to 78-year-old). Visual acuity and fundus were examined using fundus fluorescein angiography (FFA), Color Doppler Flow Imaging (CDFI), magnetic resonance angiography (MRA), and Digital subtraction angiography (DSA) etc in all patients.

RESULTS

The visual acuity was ranged from light perception to 0. 8 in all patients. The clinical features in hypoperfusion retinopathy induced neovascular glaucoma were characterized by midperipheral intraretinal hemorrhages, narrowed retinal arteries, dilated retinal veins, neovascularisation in iris and anterior chamber angle, ocular hypertension, excavation and atrophy of optic disk, and visual field defects when glaucoma progressed. All eyes have either ipsilateral common carotid artery obstruction or severe bilateral obstruction of the internal carotid arteries.

CONCLUSIONS

Neovascular glaucoma is a rare and severe complication of hypoperfusion retinopathy associated with either ipsilateral common carotid artery obstruction or severe bilateral obstruction of the internal carotid arteries. Fundus degeneration is commonly involved in one eye. The characteristic clinical features are presented during the process of the disease.

摘要

目的

分析低灌注性视网膜病变所致新生血管性青光眼的临床特征。

方法

本回顾性病例系列研究纳入18例(18只眼)低灌注性视网膜病变所致新生血管性青光眼患者。其中男性15例,女性3例;右眼10例,左眼5例。平均年龄40岁(18~78岁)。所有患者均行视力及眼底检查,并采用荧光素眼底血管造影(FFA)、彩色多普勒血流成像(CDFI)、磁共振血管造影(MRA)及数字减影血管造影(DSA)等检查。

结果

所有患者视力范围从光感至0.8。低灌注性视网膜病变所致新生血管性青光眼的临床特征表现为视网膜中周部视网膜内出血、视网膜动脉变窄、视网膜静脉扩张、虹膜及前房角新生血管形成、眼压升高、视盘凹陷及萎缩,青光眼进展时出现视野缺损。所有患眼均存在同侧颈总动脉阻塞或双侧颈内动脉严重阻塞。

结论

新生血管性青光眼是低灌注性视网膜病变的一种罕见且严重的并发症,与同侧颈总动脉阻塞或双侧颈内动脉严重阻塞相关。眼底病变通常累及单眼。在疾病过程中呈现出特征性的临床特征。

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