Beeney Joe E, Arnett Peter A
Psychology Department, The Pennsylvania State University, University Park, Pennsylvania 16802-3105, USA.
J Int Neuropsychol Soc. 2008 Nov;14(6):1057-62. doi: 10.1017/S1355617708081265.
Some researchers have suggested that general self-report depression scales may be inadequate for assessing depression among individuals with Multiple Sclerosis (MS), because many of such items represent MS disease symptoms. However, research has been mixed on this issue: whereas some studies provide support for symptom overlap, others have found opposing evidence. We investigated this issue in two different MS samples with three different strategies. We (1) examined reliable change in depression symptom categories at two time points over three years, (2) assessed the relationship between variables associated with depression and different depression symptom subscales, and (3) assessed the relationship between symptom subscales and physical disability. In each instance we found significant evidence that items meant to assess vegetative symptoms of depression may be influenced by presence of MS disease symptoms or were not associated with other core elements or central correlates of depression.
一些研究人员认为，一般的自我报告抑郁量表可能不足以评估多发性硬化症（MS）患者的抑郁情况，因为其中许多项目代表了MS疾病症状。然而，关于这个问题的研究结果并不一致：一些研究支持症状重叠的观点，而另一些研究则发现了相反的证据。我们用三种不同的策略在两个不同的MS样本中研究了这个问题。我们（1）在三年中的两个时间点检查了抑郁症状类别的可靠变化，（2）评估了与抑郁相关的变量和不同抑郁症状子量表之间的关系，以及（3）评估了症状子量表与身体残疾之间的关系。在每种情况下，我们都发现了重要证据，表明旨在评估抑郁植物神经症状的项目可能受到MS疾病症状的影响，或者与抑郁的其他核心要素或主要相关因素无关。
