Oriental Medicine Research Center of the Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan.
Evid Based Complement Alternat Med. 2009 Sep;6(3):375-8. doi: 10.1093/ecam/nem101. Epub 2007 Oct 4.
Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patients with FD from the standpoint of bowel gas retention. The bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients was significantly higher than that in healthy subjects. Two week administration of HKT in the FD patients showed a significant decrease of GVS. Furthermore, gastrointestinal symptoms, especially symptoms of abdominal pain, indigestion and constipation, all of which are closely related to abdominal bloating, improved significantly in FD patients after the administration of HKT. These results suggest that HKT improves abdominal bloating accompanied by the reduction of bowel gas in FD patients.
虽然腹胀是功能性消化不良（FD）患者最困扰的症状之一，但尚未有缓解腹胀的治疗药物。我们从肠气潴留的角度研究了汉方药半夏厚朴汤（HKT）对 FD 患者的作用。FD 患者腹部平片计算的肠气容积（气容积评分，GVS）明显高于健康受试者。FD 患者服用 HKT 两周后，GVS 显著下降。此外，胃肠症状，尤其是腹痛、消化不良和便秘的症状，这些症状均与腹胀密切相关，在 HKT 治疗后 FD 患者的症状明显改善。这些结果表明，HKT 可改善伴有肠气减少的 FD 患者的腹胀。
