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汉方药物半夏厚朴汤对功能性消化不良患者的促动力作用

Prokinetic effect of a Kampo medicine, Hange-koboku-to (Banxia-houpo-tang), on patients with functional dyspepsia.

作者信息

Oikawa T, Ito G, Koyama H, Hanawa T

机构信息

Oriental Medicine Research Center of the Kitasato Institute, Tokyo, Japan.

出版信息

Phytomedicine. 2005 Nov;12(10):730-4. doi: 10.1016/j.phymed.2005.03.001.


DOI:10.1016/j.phymed.2005.03.001
PMID:16323291
Abstract

Limited evidence is available as to whether Kampo medicine modifies gastrointestinal function in humans. We investigated the effect of a Kampo medicine, Hange-koboku-to (Banxia-houpo-tang, HKT), on patients with functional dyspepsia (FD) and on healthy volunteers with regard to gastric motility. The gastric emptying rate (GER) in FD patients was significantly lower than in the healthy subjects. GER in FD patients and in healthy volunteers showed a significant increase after 2 weeks of medication with HKT. Furthermore, gastrointestinal symptoms improved significantly in the FD patients after the administration of HKT. These results suggest that HKT improves delayed gastric emptying and acts as a prokinetic agent.

摘要

关于汉方医学是否会改变人体胃肠道功能,目前证据有限。我们研究了一种汉方药物,半夏厚朴汤(HKT),对功能性消化不良(FD)患者及健康志愿者胃动力的影响。FD患者的胃排空率(GER)显著低于健康受试者。FD患者和健康志愿者在服用HKT 2周后,GER均显著升高。此外,FD患者在服用HKT后胃肠道症状显著改善。这些结果表明,HKT可改善胃排空延迟,并起到促动力剂的作用。

相似文献

[1]
Prokinetic effect of a Kampo medicine, Hange-koboku-to (Banxia-houpo-tang), on patients with functional dyspepsia.

Phytomedicine. 2005-11

[2]
Efficacy of Rikkunshito, a traditional Japanese medicine (Kampo), in treating functional dyspepsia.

Intern Med. 2010

[3]
[Randomized controlled trial of modified banxia houpo decoction in treating functional dyspepsia patients with psychological factors].

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013-3

[4]
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[5]
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[6]
[Determination of gastric emptying time of functional dyspepsia and clinical study on therapeutic effect of Weihuigui decoction on functional dyspepsia].

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[7]
Effects of Hange-koboku-to (Banxia-houpo-tang) on neuropeptide levels in human plasma and saliva.

Biol Pharm Bull. 2003-11

[8]
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[9]
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Phytother Res. 2005-6

[10]
[Effect of Qingre Liqi Granule on clinical therapeutic efficacy, electrogastrogram and gastric emptying in patients with functional dyspepsia].

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[3]
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[7]
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[8]
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[9]
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