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自组装噬菌体M13薄膜上的定向细胞生长

Oriented cell growth on self-assembled bacteriophage M13 thin films.

作者信息

Rong Jianhua, Lee L Andrew, Li Kai, Harp Brandon, Mello Charlene M, Niu Zhongwei, Wang Qian

机构信息

Department of Materials Science and Engineering, Jinan University, Guangzhou 510632, PR China.

出版信息

Chem Commun (Camb). 2008 Nov 7(41):5185-7. doi: 10.1039/b811039e. Epub 2008 Sep 11.

DOI:10.1039/b811039e
PMID:18956063
Abstract

Fibrillar M13 bacteriophages were used as basic building blocks to generate thin films with aligned nanogrooves, which, upon chemical grafting with RGD peptides, guide cell alignment and orient the cell outgrowth along defined directions.

摘要

丝状M13噬菌体被用作基本构建单元来生成具有排列纳米凹槽的薄膜,在用RGD肽进行化学接枝后,这些薄膜可引导细胞排列并使细胞沿特定方向定向生长。

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