Zeng Wenwen, Chen Zhijian J
Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Immunity. 2008 Oct 17;29(4):513-5. doi: 10.1016/j.immuni.2008.09.010.
Two recent papers, one in this issue of Immunity (Zhong et al., 2008), report the identification of a membrane protein, termed MITA or STING, that activates the transcription factor IRF3 to induce type-I interferons to mitigate viral infection.
最近的两篇论文，其中一篇发表在本期的《免疫》杂志上（钟等人，2008年），报道了一种被称为MITA或STING的膜蛋白的鉴定，该蛋白可激活转录因子IRF3以诱导I型干扰素来减轻病毒感染。
