Toll样受体9改变了调节性T细胞的态势。
TLR9 turns the tide on Treg cells.
作者信息
Mills Kingston H G
机构信息
School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland.
出版信息
Immunity. 2008 Oct 17;29(4):518-20. doi: 10.1016/j.immuni.2008.09.005.
PMID:18957263
Abstract
In this issue of Immunity, Hall et al. (2008) demonstrate that commensal bacterial DNA can suppress Treg cell conversion via TLR9-mediated activation of lamina propria dendritic cells and thus potentially disrupt intestinal homeostasis.
摘要
在本期《免疫》杂志中，霍尔等人（2008年）证明共生细菌DNA可通过TLR9介导的固有层树突状细胞激活来抑制调节性T细胞转化，从而可能破坏肠道内稳态。
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