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[健康军事人员中乙型和丙型肝炎感染的血清流行率及危险因素]

[Seroprevalence of the infection and risk factors of hepatitis B and C in healthy military personnel].

作者信息

Chacaltana Alfonso, Espinoza Julio

机构信息

Médico Gastroenterólogo, Hospital General de Huacho.

出版信息

Rev Gastroenterol Peru. 2008 Jul-Sep;28(3):217-25.

PMID:18958136
Abstract

OBJECTIVE

Determine the prevalence of infections by the hepatitis B (HBV) and C (HCV) viruses and the risk factors associated with their acquisition in clinically healthy military personnel.

METHOD

Correlational and analytic transversal study. The population was made up of active, clinically healthy military personnel from the Peruvian Air Force that volunteered for a screening program between October and December 2007. The HBsAg and anti-HBc markers of HBV and the anti-HCV marker of HVC were evaluated.

RESULTS

Of the 3,343 military personnel studied, 93.2% (3,116) were male and 6.8% (227) were female, with an average age of 38.9+/-8.6 years (range: 18 to 60 years old), mostly non-commissioned officers (79.5%). An HBsAg prevalence of 0.33% was found, with an anti-HBc prevalence of 0.58%, while the prevalence of anti-HCV was 0.21%. The risk factor associated with active infection by HBV (HBsAG) was risky sexual behavior (OR: 8.3; IC 95%:1.6-42.4 and p=0.01). On the hand, for the past infection by HBV (anti-HBc), the associated risk factors were risky sexual behavior (OR: 6.3; IC 95%:1.7-23.4 and p=0.006) and tattoos (OR: 5.5; IC 95%:1.2-25.8 and p=0.031). No association was found between the risk factors studied and seropositivity by HCV.

CONCLUSIONS

We found a low prevalence of the serological markers of infection by hepatitis B and C viruses in active military personnel. The risk factors associated with infection by HBV were risky sexual conduct and the use of tattoos. There was no risk factor found to be associated with infection by HCV in this population.

摘要

目的

确定乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染在临床健康军事人员中的患病率及其感染相关危险因素。

方法

相关性分析横断面研究。研究对象为2007年10月至12月间自愿参加筛查项目的秘鲁空军现役临床健康军事人员。评估了HBV的HBsAg和抗-HBc标志物以及HVC的抗-HCV标志物。

结果

在3343名研究对象中,93.2%(3116人)为男性,6.8%(227人)为女性,平均年龄38.9±8.6岁(范围:18至60岁),大多数为士官(79.5%)。HBsAg患病率为0.33%,抗-HBc患病率为0.58%,而抗-HCV患病率为0.21%。与HBV活动性感染(HBsAG)相关的危险因素是危险性行为(OR:8.3;95%CI:1.6 - 42.4,p = 0.01)。另一方面,对于HBV既往感染(抗-HBc),相关危险因素是危险性行为(OR:6.3;95%CI:1.7 - 23.4,p = 0.006)和纹身(OR:5.5;95%CI:1.2 - 25.8,p = 0.031)。在所研究的危险因素与HCV血清阳性之间未发现关联。

结论

我们发现现役军事人员中乙型和丙型肝炎病毒感染血清学标志物的患病率较低。与HBV感染相关的危险因素是危险性行为和纹身。在该人群中未发现与HCV感染相关的危险因素。

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