[前往达尔富尔执行任务的塞内加尔军事人员中乙型肝炎表面抗原的流行情况及其相关因素]
[Prevalence of hepatitis B surface antigen and its associated factors in Senegalese military personnel sent on mission to Darfur].
作者信息
Diop Moustapha, Diouf Assane, Seck Said Malaobé, Lo Gora, Ka Daye, Massaly Aminata, Dieye Alassane, Fall Ndeye Maguette, Cisse-Diallo Viviane Marie Pierre, Diallo-Mbaye Khardiata, Lakhe Ndèye Aissatou, Fortes-Déguénonvo Louise, Ndour Cheikh Tidiane, Soumaré Maserigne, Seydi Moussa
机构信息
Service des Maladies Infectieuses et Tropicales, Chnu de Fann, Dakar, Sénégal.
Ecole de Santé Publique de l'Université de Montréal (ESPUM), Québec, Canada.
出版信息
Pan Afr Med J. 2017 Mar 15;26:154. doi: 10.11604/pamj.2017.26.154.11594. eCollection 2017.
INTRODUCTION
In Senegal, 85% of the adult population have been exposed to the hepatitis B virus and about 11% of them are chronic surface antigen (HBsAg) carriers. This infection is poorly documented among Senegalese Armed Forces. The aim of this study was to assess the prevalence of HBsAg in Senegalese military personnel on mission to Darfur (Sudan) and to identify its associated factors.
METHODS
We conducted a cross-sectional study among Senegalese military personnel stationed in Darfur from 1 July 2014 to 31 July 2014. HBsAg test was performed on serum of participants using immunochromatographic method. The search for associated factors was carried out using multivariate logistic regression.
RESULTS
Our study included 169 male military personnel. The average age was 36.6 ± 9.5 years. A history of familial chronic liver disease, blood exposure and sexual exposure were found in 12.4%, 24.9% and 45.6% of the study population respectively. HBsAg was found in 24 participants [14.2% (CI 95% = 8.9-19.5)]. After adjusting for potential confounding factors, age (OR = 0.9 CI 95% = 0.9-1.0), university level (OR = 9.5 CI 95% = 1.3 - 67 , 1>) and sexual exposure (OR = 3.3 <; CI 95% = 1.0 - 10.3) were independently associated with hepatitis B.
CONCLUSION
Our study shows high prevalence of HBsAg and underlines the need for further evaluation of hepatitis B in this population.
引言
在塞内加尔，85%的成年人口曾接触过乙肝病毒，其中约11%为慢性表面抗原（HBsAg）携带者。在塞内加尔武装部队中，这种感染的记录很少。本研究的目的是评估前往达尔富尔（苏丹）执行任务的塞内加尔军事人员中HBsAg的流行情况，并确定其相关因素。
方法
我们于2014年7月1日至2014年7月31日对驻扎在达尔富尔的塞内加尔军事人员进行了一项横断面研究。采用免疫层析法对参与者的血清进行HBsAg检测。使用多因素逻辑回归进行相关因素的查找。
结果
我们的研究包括169名男性军事人员。平均年龄为36.6±9.5岁。分别在12.4%、24.9%和45.6%的研究人群中发现有家族性慢性肝病病史、血液暴露和性暴露史。24名参与者中检测到HBsAg[14.2%（95%CI=8.9-19.5）]。在对潜在混杂因素进行调整后，年龄（OR=0.9，95%CI=0.9-1.0）、大学学历（OR=9.5，95%CI=1.3-67.1）和性暴露（OR=3.3，95%CI=1.0-10.3）与乙肝独立相关。
结论
我们的研究显示HBsAg的高流行率，并强调需要对该人群的乙肝情况进行进一步评估。
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